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[新鲜冰冻血浆在手术中的应用,特别提及自体新鲜冰冻血浆]

[Use of fresh frozen plasma in surgery with special reference to autologous fresh frozen plasma].

作者信息

Heim M U, Mempel W

机构信息

Transfusionszentrum, Medizinische Klinik III, Klinikum Grosshadern der Universität München.

出版信息

Infusionstherapie. 1990 Apr;17 Suppl 2:34-6.

PMID:2373546
Abstract

The use of FFP has increased dramatically in the last few years. In the majority of cases FFP is transfused in order to provide coagulation factors. Many physicians expect to get "better" blood parameters from concomitant FFP and red blood cell (RBC) transfusions. To avoid the risk of diseases transmitted by homologous blood predeposited autologous blood is useful for elective surgical patients. Intraoperative autotransfusion by blood salvage using a Cell Saver only provides autologous RBC without plasma, so predeposited autologous plasma seems to be a necessary supplement. However, according to the literature most patients receiving RBC units do not require concomitant FFP. Guidelines for the use of FFP based on controlled clinical trials are necessary.

摘要

在过去几年中,新鲜冰冻血浆(FFP)的使用急剧增加。在大多数情况下,输注FFP是为了提供凝血因子。许多医生期望通过同时输注FFP和红细胞(RBC)获得“更好”的血液参数。为避免同源血传播疾病的风险,预存自体血对择期手术患者有用。使用血液回收机进行术中自体输血仅提供无血浆的自体RBC,因此预存自体血浆似乎是必要的补充。然而,根据文献,大多数接受RBC单位输血的患者不需要同时输注FFP。基于对照临床试验的FFP使用指南是必要的。

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