Bay Jacques-Olivier, Guièze Romain, Ravinet Aurélie, Lemal Richard, Xhaard Aliénor, Bailly Sébastien, Moluçon-Chabrot Cécile, Hermet Eric, Biau Julian, Verrelle Pierre, Peffault de Latour Régis, Tournilhac Olivier
CHU Clermont-Ferrand, service d'hématologie clinique adulte et de thérapie cellulaire, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand cedex 01, France.
Bull Cancer. 2013 Jun;100(6):587-99. doi: 10.1684/bdc.2013.1751.
Hematology Oncology has a rich history including few crucial therapeutic innovations. These were possible because of the evolution of the cell and molecular biology allowing a better understanding of basic mechanisms of cancerogenesis. We propose here to summarize the most important therapeutic innovations since the beginning of Hematology/Oncology history. We also describe evolution of therapeutic strategies themselves. New insights and therapeutic perspectives for next future are also discussed.
血液学肿瘤学有着丰富的历史，其中包括一些关键的治疗创新。这些创新之所以成为可能，是因为细胞和分子生物学的发展使人们能够更好地理解癌症发生的基本机制。我们在此提议总结自血液学/肿瘤学历史开端以来最重要的治疗创新。我们还将描述治疗策略本身的演变。同时也会讨论未来的新见解和治疗前景。
