Soonthornsit Jeerawat, Banlunara Wijit, Niyomthum Waree, Pusoonthornthum Rosama
1Department of Veterinary Medicine, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
J Feline Med Surg. 2013 Dec;15(12):1154-9. doi: 10.1177/1098612X13491758. Epub 2013 Jun 4.
A 5-year-old, female neutered Persian cat was admitted to the Small Animal Hospital (Chulalongkorn University, Bangkok, Thailand) with clinical signs of dysuria, haematuria and partial urethral obstruction that had manifested over several months. The animal also had hyperkalaemia and severe azotaemia at the time of presentation. Urinalysis showed haematuria, pyuria and the presence of several transitional cells. In addition, ultrasonography demonstrated an extraluminal mass between the neck of urinary bladder and the colon. Fine-needle aspiration of the mass revealed a fungal form with branching and septate hyphae. Consequently, itraconazole treatment was prescribed and clinical signs of improvement were seen after 7 days. However, 1 month later, the cat died of acute anaemia. Necropsy revealed the presence of extraluminal multifocal fungal granuloma at the neck of the urinary bladder, and contracted kidneys. Histopathological analysis of the fungal granuloma was found to be composed of branching, septate hyphal fungi together with inflammatory cells. Subsequent fungal culture and identification revealed this to be a species of Penicillium.
一只5岁已绝育的雌性波斯猫被送往泰国曼谷朱拉隆功大学小动物医院，它出现排尿困难、血尿和部分尿道梗阻的临床症状已有数月。就诊时该动物还伴有高钾血症和严重氮质血症。尿液分析显示有血尿、脓尿以及几个移行细胞。此外，超声检查显示膀胱颈部和结肠之间有一个腔外肿块。对该肿块进行细针穿刺抽吸，发现一种具有分支和分隔菌丝的真菌形态。因此，开了伊曲康唑进行治疗，7天后可见临床症状有所改善。然而，1个月后，这只猫死于急性贫血。尸检发现膀胱颈部有腔外多灶性真菌肉芽肿，以及萎缩的肾脏。对真菌肉芽肿进行组织病理学分析，发现其由分支、分隔的菌丝真菌和炎症细胞组成。随后的真菌培养和鉴定显示这是一种青霉菌。
