Whitney Beth L, Broussard John, Stefanacci Joseph D
Veterinary Referral and Emergency Center, 123 West Cedar Street, Norwalk, CT, USA.
J Feline Med Surg. 2005 Feb;7(1):53-8. doi: 10.1016/j.jfms.2004.02.004.
Fungal rhinitis is uncommon in the cat and cases of nasal aspergillosis-penicilliosis have been rarely reported. Signs of fungal rhinitis include epistaxis, sneezing, mucopurulent nasal discharge and exophthalmos. Brachycephalic feline breeds seem to be at increased risk for development of nasal aspergillosis-penicilliosis. Computed tomography (CT) imaging and rhinoscopy are useful in assessing the extent of the disease and in obtaining diagnostic samples. Fungal culture may lead to false negative or positive results and must be used in conjunction with other diagnostic tests. Serological testing was not useful in two cats tested. The cats in this study were treated with oral itraconazole therapy. When itraconazole therapy was discontinued prematurely, clinical signs recurred. Hepatotoxicosis is a possible sequel to itraconazole therapy.
真菌性鼻炎在猫中并不常见,鼻曲霉菌病-青霉病的病例鲜有报道。真菌性鼻炎的症状包括鼻出血、打喷嚏、黏液脓性鼻分泌物和眼球突出。短头猫品种似乎患鼻曲霉菌病-青霉病的风险更高。计算机断层扫描(CT)成像和鼻镜检查有助于评估疾病的范围并获取诊断样本。真菌培养可能会导致假阴性或假阳性结果,必须与其他诊断测试结合使用。血清学检测对两只受试猫无效。本研究中的猫接受了口服伊曲康唑治疗。过早停用伊曲康唑治疗后,临床症状复发。肝毒性是伊曲康唑治疗可能出现的后遗症。