Rööser B, Berg N O, Ranstam J, Rydholm A, Willén H
Department of Orthopaedics, University of Lund, Sweden.
Int Orthop. 1990;14(2):199-204. doi: 10.1007/BF00180129.
Using the Cox proportional hazards model, and considering tumour necrosis and vascular invasion by tumour as additional factors in assessment, a series of 88 patients with primary Grade III and IV soft tissue sarcomas of the locomotor system was analysed for factors associated with death due to the tumour. Grade IV malignancy, a tumour size larger than 10 cm., tumour necrosis, and vascular invasion by tumour cells were significant risk factors. Patients with 0 or 1 risk factor, one half of the cases, had a 3 year survival rate of more than 90%, whereas the figure was 65% for those with 2 risk factors and 20% for those with 3 or 4 risk factors.
运用Cox比例风险模型，并将肿瘤坏死和肿瘤血管侵犯作为评估中的附加因素，对88例原发性运动系统III级和IV级软组织肉瘤患者进行了分析，以寻找与肿瘤相关死亡的因素。IV级恶性肿瘤、肿瘤大小大于10厘米、肿瘤坏死以及肿瘤细胞血管侵犯是显著的风险因素。具有0或1个风险因素（即一半病例）的患者3年生存率超过90%，而具有2个风险因素的患者这一数字为65%，具有3或4个风险因素的患者则为20%。
