Department of Psychiatry and Psychotherapy, University Hospital of Friedrich Alexander University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany,
J Neural Transm (Vienna). 2013 Oct;120(10):1507-10. doi: 10.1007/s00702-013-1043-8. Epub 2013 Jun 5.
In the present study, the effects of vagus nerve stimulation (VNS) on the resting motor threshold (rMT) of patients treated with repetitive transcranial magnetic stimulation were evaluated. Patients showed a significant decrease in the rMT during VNS-on stimulation. VNS was the only significant factor affecting rMT changes and did not appear to be a static variable. Further studies should focus on the effect of VNS on neural neurogenesis in depressive disorders, and the effects of other treatment options for major depressive disorder on the rMT should also be determined.
在本研究中,评估了迷走神经刺激(VNS)对接受重复经颅磁刺激治疗的患者静息运动阈值(rMT)的影响。患者在 VNS 开启刺激时表现出 rMT 的显著降低。VNS 是唯一显著影响 rMT 变化的因素,且似乎不是一个静态变量。进一步的研究应集中在 VNS 对抑郁障碍中神经发生的影响上,还应确定其他治疗选择对 rMT 的影响。