Kyriazidou A, Haider D, Mason C, Parekh S, Bloch-Zupan A
Eastman Dental Institute, University College of London, 256 Gray's Inn Road, London, WC1X 8LD, UK,
Eur Arch Paediatr Dent. 2013 Dec;14(6):411-6. doi: 10.1007/s40368-013-0043-6. Epub 2013 Jun 5.
Macrodontia or megadontia is a rare dental anomaly that refers to teeth that appear larger than normal. Generalised macrodontia may be associated with certain medical conditions and syndromes. Isolated macrodontia involves single teeth, might be the result of teeth fusion and is mainly seen in the incisor area.
This paper describes two unrelated cases presenting with bilateral macrodont second lower premolars and the treatment provided. One case demonstrated the anomaly in both the patient and his father.
This case report suggests for the first time in the literature the genetic aetiology and heritability, as a possible autosomal dominant trait, of this rare dental anomaly.
巨牙症是一种罕见的牙齿异常，指牙齿看起来比正常的大。全身性巨牙症可能与某些医学病症和综合征有关。孤立性巨牙症累及单个牙齿，可能是牙齿融合的结果，主要见于切牙区。
本文描述了两例双侧下颌第二前磨牙巨牙症的无关病例及所提供的治疗。其中一例在患者及其父亲身上均表现出该异常。
本病例报告首次在文献中提示了这种罕见牙齿异常的遗传病因及遗传性，可能为常染色体显性性状。
