Deshingkar S A, Barpande S R, Bhavthankar J D
Department of Oral Pathology and Microbiology, Government Dental College and Hospital, Aurangabad, Maharashtra, India.
Contemp Clin Dent. 2011 Jul;2(3):261-4. doi: 10.4103/0976-237X.86492.
Congenital hemifacial hyperplasia (CHH) is a rare congenital malformation characterized by marked unilateral overdevelopment of hard and soft tissues of the face. Asymmetry in CHH is usually evident at birth and accentuated with age, especially at puberty. The affected side grows at a rate proportional to the nonaffected side so that the disproportion is maintained thr oughout the life. Multisystem involvement has resulted in etiological heterogeneity including heredity, chromosomal abnormalities, atypical forms of twinning, altered intrauterine environment, and endocrine dysfunctions; however, no single theory explains the etiology adequately. Deformities of all tissues of face, including teeth and their related tissues in the jaw, are key findings for correct diagnosis of CHH. Here an attempt has been made to present a case of CHH with its archetypal features and to supplement existing clinical knowledge.
先天性半侧颜面增生症（CHH）是一种罕见的先天性畸形，其特征为面部软硬组织明显单侧过度发育。CHH的不对称通常在出生时就很明显，并随着年龄增长而加剧，尤其是在青春期。患侧以与未患侧成比例的速度生长，因此这种不对称在一生中都会持续存在。多系统受累导致病因异质性，包括遗传、染色体异常、非典型双胎形式、子宫内环境改变和内分泌功能障碍；然而，没有单一理论能充分解释其病因。面部所有组织的畸形，包括牙齿及其颌骨相关组织的畸形，是正确诊断CHH的关键发现。本文试图呈现一例具有典型特征的CHH病例，并补充现有的临床知识。
