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大鼠使用微型皮片和中国式混合皮片的瘢痕挛缩比较。

Comparison of scar contracture with the use of microskin and Chinese-type intermingled skin grafts on rats.

作者信息

Yeh F L, Yu G S, Fang C H, Carey M, Alexander J W, Robb E C

机构信息

Shriners Burns Institute, Cincinnati, OH 45219.

出版信息

J Burn Care Rehabil. 1990 May-Jun;11(3):221-3. doi: 10.1097/00004630-199005000-00007.

Abstract

Wounds that were measured precisely 4 x 5 cm in size were created over the dorsal surfaces of rats. The defects were grafted with the use of either the microskin or Chinese technique of intermingled auto/allograft with an expansion ratio of 10:1. The size of the grafted wound of each rat was recorded on the fifth graft day after grafting and then weekly for 11 weeks. The extent of scar contracture on each rat was calculated weekly as a percentage of the original size. The results showed that the scar contracture associated with the Chinese type of intermingled auto/allograft transplantation was less than that associated with the microskin technique. The healing process in both forms of grafting was uneventful.

摘要

在大鼠背部制造尺寸精确为4×5厘米的伤口。使用微型皮肤或中国的自体/异体混合移植技术(扩张比例为10:1)对缺损进行移植。在移植后的第5个移植日记录每只大鼠移植伤口的大小,然后在接下来的11周内每周记录一次。每周计算每只大鼠的瘢痕挛缩程度,以原始大小的百分比表示。结果表明,与中国类型的自体/异体混合移植相关的瘢痕挛缩小于与微型皮肤技术相关的瘢痕挛缩。两种移植形式的愈合过程均顺利。

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