伤口愈合的微移植概念：策略与应用
The micrograft concept for wound healing: strategies and applications.
作者信息
Biswas Atanu, Bharara Manish, Hurst Craig, Armstrong David G, Rilo Horacio
机构信息
College of Medicine, Department of Surgery, Center for Cellular Transplantation, University of Arizona, Tucson, Arizona 85724, USA.
出版信息
J Diabetes Sci Technol. 2010 Jul 1;4(4):808-19. doi: 10.1177/193229681000400407.
Abstract
The standard of care for wound coverage is to use an autologous skin graft. However, large or chronic wounds become an exceptionally challenging problem especially when donor sites are limited. It is important that the clinician be aware of various treatment modalities for wound care and incorporate those methods appropriately in the proper clinical context. This report reviews an alternative to traditional meshed skin grafting for wound coverage: micrografting. The physiological concept of micrografting, along with historical context, and the evolution of the technique are discussed, as well as studies needed for micrograft characterization and future applications of the technique.
摘要
伤口覆盖的护理标准是使用自体皮肤移植。然而，大面积或慢性伤口成为一个极具挑战性的问题，尤其是在供体部位有限的情况下。临床医生必须了解伤口护理的各种治疗方式，并在适当的临床环境中恰当地运用这些方法。本报告回顾了一种用于伤口覆盖的传统网状皮肤移植替代方法：微移植。文中讨论了微移植的生理概念、历史背景以及该技术的演变，还探讨了微移植特性鉴定所需的研究以及该技术的未来应用。
相似文献
1
The micrograft concept for wound healing: strategies and applications.
J Diabetes Sci Technol. 2010 Jul 1;4(4):808-19. doi: 10.1177/193229681000400407.
2
Meek micrografting history, indications, technique, physiology and experience: a review article.
J Wound Care. 2018 Feb 1;27(Sup2):S12-S18. doi: 10.12968/jowc.2018.27.Sup2.S12.
3
Evaluation of the efficacy of cell and micrograft transplantation for full-thickness wound healing.
J Surg Res. 2018 Jul;227:35-43. doi: 10.1016/j.jss.2018.02.004. Epub 2018 Mar 6.
4
Pixel Grafting: An Evolution of Mincing for Transplantation of Full-Thickness Wounds.
Plast Reconstr Surg. 2016 Jan;137(1):92e-99e. doi: 10.1097/PRS.0000000000001871.
5
The Meek micrograft technique for burns; review on its outcomes: Searching for the superior skin grafting technique.
Burns. 2022 Sep;48(6):1287-1300. doi: 10.1016/j.burns.2022.05.011. Epub 2022 May 13.
6
Technical tips to enhance micrografting results in burn surgery.
Burns. 2017 Aug;43(5):983-986. doi: 10.1016/j.burns.2017.01.030. Epub 2017 Apr 22.
7
[From wound healing to modern tissue engineering of the skin. A historical review on early techniques of cell and tissue culture].
Hautarzt. 2002 Nov;53(11):751-60. doi: 10.1007/s00105-002-0445-6.
8
Lower donor site morbidity and higher patient satisfaction with epidermal grafting in comparison to split thickness skin grafting: A randomized controlled trial (EPIGRAAFT Trial).
J Plast Reconstr Aesthet Surg. 2020 Aug;73(8):1556-1564. doi: 10.1016/j.bjps.2020.03.006. Epub 2020 Mar 16.
9
Systematic review and meta-analysis of the efficacy of epidermal grafting for wound healing.
Int Wound J. 2017 Dec;14(6):921-928. doi: 10.1111/iwj.12729. Epub 2017 Feb 15.
10
The use of glycerol-preserved allografts in the Beverwijk Burn Centre: a retrospective study.
Burns. 2002 Oct;28 Suppl 1:S2-9. doi: 10.1016/s0305-4179(02)00084-0.
引用本文的文献
1
Novel Techniques in Fractional Skin Replacement.
Eur Burn J. 2025 Mar 6;6(1):13. doi: 10.3390/ebj6010013.
2
A perioperative layered autologous tissue expansion graft for hollow organ repair.
Heliyon. 2024 Jan 24;10(3):e25275. doi: 10.1016/j.heliyon.2024.e25275. eCollection 2024 Feb 15.
3
Safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars.
Heliyon. 2023 Jun 7;9(6):e16992. doi: 10.1016/j.heliyon.2023.e16992. eCollection 2023 Jun.
4
Accelerating cutaneous healing in a rodent model of type II diabetes utilizing non-invasive focused ultrasound targeted at the spleen.
Front Neurosci. 2022 Nov 17;16:1039960. doi: 10.3389/fnins.2022.1039960. eCollection 2022.
5
Promotive effects of four herbal medicine ARCC on wound healing in mice and human.
Health Sci Rep. 2022 Apr 20;5(3):e494. doi: 10.1002/hsr2.494. eCollection 2022 May.
6
A Histological Evaluation of Artificial Dermal Scaffold Used in Micrograft Treatment: A Case Study of Micrograft and NPWT Performed on a Postoperative Ulcer Formation after Tumor Resection.
Medicina (Kaunas). 2022 Jan 4;58(1):73. doi: 10.3390/medicina58010073.
7
Large full-thickness wounded skin regeneration using 3D-printed elastic scaffold with minimal functional unit of skin.
J Tissue Eng. 2022 Jan 6;13:20417314211063022. doi: 10.1177/20417314211063022. eCollection 2022 Jan-Dec.
8
Immune tolerance of allogeneic haematopoietic cell transplantation supports donor epidermal grafting of recessive dystrophic epidermolysis bullosa chronic wounds.
Br J Dermatol. 2021 Jun;184(6):1161-1169. doi: 10.1111/bjd.19503. Epub 2020 Dec 14.
9
Tissue regeneration: an overview from stem cells to micrografts.
J Int Med Res. 2020 Jun;48(6):300060520914794. doi: 10.1177/0300060520914794.
10
Activator Protein-1 Transcriptional Activity Drives Soluble Micrograft-Mediated Cell Migration and Promotes the Matrix Remodeling Machinery.
Stem Cells Int. 2019 Dec 31;2019:6461580. doi: 10.1155/2019/6461580. eCollection 2019.
本文引用的文献
1
Co-graft of acellular dermal matrix and autogenous microskin in a child with extensive burns.
Ann Burns Fire Disasters. 2008 Jun 30;21(2):102-6.
2
A New Method of Grafting.
Br Med J. 1943 Jun 12;1(4301):723-4. doi: 10.1136/bmj.1.4301.723.
3
Wound chemotherapy by the use of negative pressure wound therapy and infusion.
Eplasty. 2010 Jan 8;10:e9.
4
Experience with biobrane: uses and caveats for success.
Eplasty. 2009 Jun 26;9:e25.
5
Investigating human microskin grafting technique in a new experimental model.
Burns. 2009 Aug;35(5):681-6. doi: 10.1016/j.burns.2008.09.016. Epub 2009 Feb 10.
6
Adult burn patients with more than 60% TBSA involved-Meek and other techniques to overcome restricted skin harvest availability--the Viennese Concept.
J Burn Care Res. 2009 Mar-Apr;30(2):231-42. doi: 10.1097/BCR.0b013e318198a2d6.
7
Cultured epidermal autografts in combination with MEEK Micrografting technique in the treatment of major burn injuries.
Med J Malaysia. 2008 Jul;63 Suppl A:44.
8
A systematic review of the effectiveness of interventions to enhance the healing of chronic ulcers of the foot in diabetes.
Diabetes Metab Res Rev. 2008 May-Jun;24 Suppl 1:S119-44. doi: 10.1002/dmrr.825.
9
Vacuum assisted closure device improves the take of mesh grafts in chronic leg ulcer patients.
Dermatology. 2008;216(3):250-6. doi: 10.1159/000112937. Epub 2008 Jan 17.
10
Nanofiber technology: designing the next generation of tissue engineering scaffolds.
Adv Drug Deliv Rev. 2007 Dec 10;59(14):1413-33. doi: 10.1016/j.addr.2007.04.022. Epub 2007 Aug 25.
Zotero 插件