Fang C H, Alexander J W
Shriners Burns Institute, Cincinnati, Ohio.
Burns. 1990 Jun;16(3):190-2. doi: 10.1016/0305-4179(90)90037-w.
The wound contraction associated with a new grafting technique, transplantation of microskin autografts with overlaid skin allograft, was evaluated in a rat model. Male inbred Lewis rats were used as microskin autograft recipients while Buffalo rats were used as allogeneic skin graft donors providing a sheet allograft for overlay. This technique was compared with the use of sheet isografts. Wound contraction was observed for 4 months. The results showed that the application of autologous microskin grafting with allograft overlay was associated with more scar contraction than was the use of a sheet isograft. Maximum contraction to 43 per cent of the original size appeared at 7 weeks postgrafting in the microskin grafting group, while in the sheet isografting group the greatest contraction occurred at 4 weeks postgrafting when it retained 72 per cent of the original size.
在大鼠模型中评估了一种新的移植技术——自体微小皮片移植联合同种异体皮肤覆盖移植所伴随的伤口收缩情况。雄性近交系Lewis大鼠作为自体微小皮片移植的受体，而布法罗大鼠作为同种异体皮肤移植的供体，提供一片用于覆盖的同种异体移植皮片。将该技术与使用同种同基因皮片进行比较。观察伤口收缩4个月。结果表明，自体微小皮片移植联合同种异体移植皮片覆盖所引起的瘢痕收缩比使用同种同基因皮片更多。微小皮片移植组在移植后7周出现最大收缩，收缩至原始大小的43%，而在同种同基因皮片移植组中，最大收缩发生在移植后4周，此时保留原始大小的72%。
