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肥胖与肾脏病学:知识和实践模式调查结果。

Obesity and nephrology: results of a knowledge and practice pattern survey.

机构信息

Division of Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden.

出版信息

Nephrol Dial Transplant. 2013 Nov;28 Suppl 4:iv99-104. doi: 10.1093/ndt/gft193. Epub 2013 Jun 4.

Abstract

BACKGROUND

Obesity, the largest epidemic of modern time, carries a markedly increased risk of type-2 diabetes, cancer, fatty liver, sleep apnea, hypertension, dyslipidemia and atherosclerotic cardiovascular disease. In addition, obesity increases the risk of chronic kidney disease (CKD) and its progression to end-stage renal disease (ESRD). There are limited data regarding the basic knowledge of nephrologists on how to assess and manage obesity in the setting of CKD.

METHODS

To learn more about practice patterns among nephrologists, a survey on obesity was published online in NDT-Educational between 8 November 2012 and 31 January 2013. Three-hundred and ninety-nine responses were received mostly from nephrologists in Europe (57%), South and Central America (12%) and the Middle East (10%). The majority practiced in clinical nephrology (64%) and outpatient dialysis clinics (23%). Whereas 54% of the participants worked in hospitals, 31% worked in academic centers.

RESULTS

Most participants stated that the number of obese patients has increased both among their CKD stage 2-5 patients and in their dialysis clinics during the last 10 years. For routine estimation of body fat content in the dialysis clinic, the majority of nephrologists (43%) still rely on the body mass index (BMI). A majority (72%) does not think that weight gain should be promoted in dialysis patients with a BMI of <35 kg/m(2). The survey also showed that 30% of the responders did not have any predetermined cut-off level for BMI. However, 29% used a cut-off level of 35 kg/m(2) and 27% used a cut-off level of 30 kg/m(2) for approval for kidney transplantation in their clinics.

CONCLUSIONS

The level of understanding of the intricacies of obesity in the setting of CKD needs improvement among nephrologists. Similarly, there is no consensus regarding weight management strategies in CKD patients with obesity. Studies are needed in this orphan area of renal research.

摘要

背景

肥胖是现代最大的流行病,它显著增加了 2 型糖尿病、癌症、脂肪肝、睡眠呼吸暂停、高血压、血脂异常和动脉粥样硬化性心血管疾病的风险。此外,肥胖增加了慢性肾脏病(CKD)及其进展为终末期肾病(ESRD)的风险。关于肾病学家如何在 CKD 背景下评估和管理肥胖,数据有限。

方法

为了更多地了解肾病学家的实践模式,一项关于肥胖的调查于 2012 年 11 月 8 日至 2013 年 1 月 31 日在 NDT-Educational 在线发表。共收到 399 份回复,主要来自欧洲(57%)、南美洲和中美洲(12%)和中东(10%)的肾病学家。大多数人在临床肾脏病学(64%)和门诊透析诊所(23%)工作。54%的参与者在医院工作,31%在学术中心工作。

结果

大多数参与者表示,在过去 10 年中,他们的 CKD 2-5 期患者和透析诊所中的肥胖患者数量都有所增加。对于在透析诊所常规估计体脂肪含量,大多数肾病学家(43%)仍然依赖体重指数(BMI)。大多数(72%)人认为在 BMI<35kg/m2的透析患者中不应促进体重增加。调查还显示,30%的应答者没有任何预定的 BMI 截止水平。然而,29%的人在他们的诊所使用 35kg/m2的截止水平,27%的人使用 30kg/m2的截止水平来批准肾脏移植。

结论

肾病学家对 CKD 背景下肥胖的复杂性的理解水平需要提高。同样,对于肥胖的 CKD 患者的体重管理策略也没有共识。在这个肾脏研究的孤儿领域需要进行研究。

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