Zhao Xiaohui, Huang Lan
Department of Cardiology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, P.R. China.
Exp Ther Med. 2013 May;5(5):1273-1276. doi: 10.3892/etm.2013.984. Epub 2013 Feb 28.
The heart has been regarded as a terminally differentiated organ for decades. There are numerous indicators for the potency of myocardial regeneration, which opens up new avenues for the treatment of heart disease. Cardiac stem cells (CSCs) have been discovered in the human heart and they play a vital role in myocardial regeneration. This review discusses the distribution, properties and proliferation of CSCs in the myocardium of patients with heart disease. Additionally, the potency of myocardial regeneration in patients with heart disease is discussed.
几十年来,心脏一直被视为一种终末分化器官。心肌再生能力有众多指标,这为心脏病治疗开辟了新途径。人们已在人类心脏中发现心脏干细胞(CSCs),它们在心肌再生中发挥着至关重要的作用。本综述讨论了心脏病患者心肌中CSCs的分布、特性和增殖情况。此外,还讨论了心脏病患者的心肌再生能力。