一种新型局部用富氧油治疗急性肌腱病和扭伤疼痛的疗效评估。
Evaluation of a novel topical essential oxygen oil for the treatment of pain in acute tendinopathy and sprains.
作者信息
Pappagallo Marco, Leslie John B, Raffa Robert B, Kash Peter, Fleischer Charles, Sinclair Nicholas, Labhestwar Sumedha, Di Lorenzo Luigi, Tabor Aaron
机构信息
Department of Anesthesiology, Mount Sinai School of Medicine, New York, New York.
出版信息
Muscles Ligaments Tendons J. 2011 Oct 30;1(1):25-30. Print 2011 Jan.
Topical analgesics may play an increasingly important role in managing acute and chronic pain as acetaminophen, NSAIDs, and opioid drugs come under heightened scrutiny. This article reviews studies about essential oxygen oil, a topical over-the-counter (OTC) analgesic new to the American market but available for many years in Europe. Prospective studies evaluating the oil's safety and efficacy in acute and chronic pain patients, a dermatological study in which healthy subjects served as their own controls, and a post-marketing surveillance study were considered. These studies found the novel essential oxygen oil to be safe and effective in a variety of acute and chronic pain syndromes as well as being well tolerated with few side effects. Its mechanism of action is not understood and further study is warranted. Essential oxygen oil is safe and effective for the treatment of pain associated with many common conditions, including tendinopathy, arthritis, sprains, and others.
随着对乙酰氨基酚、非甾体抗炎药和阿片类药物的审查日益严格，局部用镇痛药在急性和慢性疼痛管理中可能发挥越来越重要的作用。本文回顾了关于基本氧气油的研究，这是一种在美国市场上全新的非处方（OTC）局部用镇痛药，但在欧洲已上市多年。文中考虑了评估该油在急性和慢性疼痛患者中的安全性和有效性的前瞻性研究、以健康受试者自身作为对照的皮肤病学研究以及上市后监测研究。这些研究发现，这种新型基本氧气油在多种急性和慢性疼痛综合征中安全有效，耐受性良好，副作用较少。其作用机制尚不清楚，有必要进一步研究。基本氧气油对于治疗与许多常见病症相关的疼痛是安全有效的，这些病症包括肌腱病、关节炎、扭伤等。
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