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局部应用聚多卡醇联合静态拉伸治疗肌腱病:一项前瞻性初步研究。

Topical polidocanol application in combination with static stretching in tendinopathies: a prospective pilot study.

作者信息

Gatz Matthias, Schrading Simone, Dirrichs Timm, Betsch Marcel, Tingart Markus, Rath Björn, Kuhl Christiane, Quack Valentin

机构信息

Department of Orthopaedics, RWTH Aachen, Germany.

Department of Diagnostic and Interventional Radiology, RWTH Aachen University Hospital, Germany.

出版信息

Muscles Ligaments Tendons J. 2017 May 10;7(1):88-97. doi: 10.11138/mltj/2017.7.1.088. eCollection 2017 Jan-Mar.

Abstract

BACKGROUND

Highly operator-based injection therapy with vasosclerosing and anesthetic polidocanol is used for tendinopathies. This pilot-study evaluates the topical application of polidocanol gel.

METHODS

Prospective case series. 39 patients with tendinopathies (14 Achilles, 14 patella, 11 wrist extensors) with a symptom duration > 6 months were included. Polidocanol and static stretching were the therapy in the first 2 weeks, while static stretching was continuously performed for 6 months. Clinical outcome was evaluated with VISA-A, VISA-P and DASH Scores and sonographically with B-Mode (B-Mode), Power Doppler (PD) and Shearwave Elastography (SWE).

RESULTS

22 patients clinically improved (>+10 score points), 11 patients were without improvement (<+ 10) and 1 patient worsened during 6 months. The VISA-A Score increased in average 19 points from 56 to 75 (p< 0.01), VISA-P Score increased 13 points from 59 to 72 (p< 0,01) and the DASH-Score decreased 20 points from 40 to 20 (p< 0,01). SWE correlates better than B-Mode or PD with symptom improvement.

CONCLUSION

The combination of static training and topical polidocanol application seems to be successful in the treatment of tendinopathies. Further RCT studies need to evaluate the efficiency of topical polidocanol application. SWE is a more sensitive tool to describe symptom development than PD or B-Mode.

LEVEL OF EVIDENCE

IV.

摘要

背景

基于操作者的高剂量硬化剂和麻醉剂聚多卡醇注射疗法用于治疗肌腱病。本初步研究评估聚多卡醇凝胶的局部应用。

方法

前瞻性病例系列研究。纳入39例症状持续时间>6个月的肌腱病患者(14例跟腱、14例髌骨、11例腕伸肌)。前2周采用聚多卡醇和静态拉伸治疗,而静态拉伸持续进行6个月。用VISA - A、VISA - P和DASH评分评估临床结局,并通过B超(B - Mode)、功率多普勒(PD)和剪切波弹性成像(SWE)进行超声检查。

结果

22例患者临床症状改善(评分增加>10分),11例患者无改善(评分增加<10分),1例患者在6个月内病情恶化。VISA - A评分平均从56分增加到75分(增加19分,p<0.01),VISA - P评分从59分增加到72分(增加13分,p<0.01),DASH评分从40分降至20分(降低20分,p<0.01)。与症状改善的相关性方面,SWE优于B超或PD。

结论

静态训练和局部应用聚多卡醇联合治疗肌腱病似乎有效。需要进一步的随机对照试验研究来评估局部应用聚多卡醇的疗效。与PD或B超相比,SWE是描述症状发展更敏感的工具。

证据级别

IV级

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