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Toggling in the spliceosome.

作者信息

Abelson John

出版信息

Nat Struct Mol Biol. 2013 Jun;20(6):645-7. doi: 10.1038/nsmb.2603.

DOI:10.1038/nsmb.2603

PMID:23739164

Abstract

摘要

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本文引用的文献

A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.

Nat Struct Mol Biol. 2013 Jun;20(6):728-34. doi: 10.1038/nsmb.2556. Epub 2013 May 19.

Now on display: a gallery of group II intron structures at different stages of catalysis.

Mob DNA. 2013 May 1;4(1):14. doi: 10.1186/1759-8753-4-14.

Structural biology: Spliceosome's core exposed.

Nature. 2013 Jan 31;493(7434):615-6. doi: 10.1038/nature11857. Epub 2013 Jan 23.

Crystal structure of Prp8 reveals active site cavity of the spliceosome.

Nature. 2013 Jan 31;493(7434):638-43. doi: 10.1038/nature11843. Epub 2013 Jan 23.

Visualizing group II intron catalysis through the stages of splicing.

Cell. 2012 Oct 26;151(3):497-507. doi: 10.1016/j.cell.2012.09.033.

The spliceosome: design principles of a dynamic RNP machine.

Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009.

Is the spliceosome a ribonucleoprotein enzyme?

Nat Struct Mol Biol. 2008 Dec;15(12):1235-7. doi: 10.1038/nsmb1208-1235.

Structural elucidation of a PRP8 core domain from the heart of the spliceosome.

Nat Struct Mol Biol. 2008 Nov;15(11):1199-205. doi: 10.1038/nsmb.1505. Epub 2008 Oct 2.

Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins.

Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13817-22. doi: 10.1073/pnas.0805960105. Epub 2008 Sep 8.

Crystal structure of a self-spliced group II intron.

Science. 2008 Apr 4;320(5872):77-82. doi: 10.1126/science.1153803.

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相似文献

Toggling in the spliceosome.

Nat Struct Mol Biol. 2013 Jun;20(6):645-7. doi: 10.1038/nsmb.2603.

A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.

Nat Struct Mol Biol. 2013 Jun;20(6):728-34. doi: 10.1038/nsmb.2556. Epub 2013 May 19.

The 3.8 Å structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis.

Science. 2016 Jan 29;351(6272):466-75. doi: 10.1126/science.aad6466. Epub 2016 Jan 7.

A close-up look at the spliceosome, at last.

Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4288-4293. doi: 10.1073/pnas.1700390114. Epub 2017 Apr 13.

How Is Precursor Messenger RNA Spliced by the Spliceosome?

Annu Rev Biochem. 2020 Jun 20;89:333-358. doi: 10.1146/annurev-biochem-013118-111024. Epub 2019 Dec 9.

Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8.

RNA. 2009 Jul;15(7):1292-304. doi: 10.1261/rna.1347409. Epub 2009 May 15.

Structural dynamics of the N-terminal domain and the Switch loop of Prp8 during spliceosome assembly and activation.

Nucleic Acids Res. 2018 May 4;46(8):3833-3840. doi: 10.1093/nar/gky242.

Sad1 counteracts Brr2-mediated dissociation of U4/U6.U5 in tri-snRNP homeostasis.

Mol Cell Biol. 2014 Jan;34(2):210-20. doi: 10.1128/MCB.00837-13. Epub 2013 Nov 4.

The nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cells.

RNA. 2013 Aug;19(8):1054-63. doi: 10.1261/rna.037069.112. Epub 2013 Jun 21.

Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing.

EMBO J. 2002 Mar 1;21(5):1148-57. doi: 10.1093/emboj/21.5.1148.

引用本文的文献

RNase H As Gene Modifier, Driver of Evolution and Antiviral Defense.

Front Microbiol. 2017 Sep 14;8:1745. doi: 10.3389/fmicb.2017.01745. eCollection 2017.

Conformational dynamics of stem II of the U2 snRNA.

RNA. 2016 Feb;22(2):225-36. doi: 10.1261/rna.052233.115. Epub 2015 Dec 2.

Structural studies of the spliceosome: zooming into the heart of the machine.

Curr Opin Struct Biol. 2014 Apr;25(100):57-66. doi: 10.1016/j.sbi.2013.12.002. Epub 2014 Jan 28.

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Nucleic Acids Res. 2014 Feb;42(3):1947-58. doi: 10.1093/nar/gkt1051. Epub 2013 Nov 6.

本文引用的文献

A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.

Nat Struct Mol Biol. 2013 Jun;20(6):728-34. doi: 10.1038/nsmb.2556. Epub 2013 May 19.

Now on display: a gallery of group II intron structures at different stages of catalysis.

Mob DNA. 2013 May 1;4(1):14. doi: 10.1186/1759-8753-4-14.

Structural biology: Spliceosome's core exposed.

Nature. 2013 Jan 31;493(7434):615-6. doi: 10.1038/nature11857. Epub 2013 Jan 23.

Crystal structure of Prp8 reveals active site cavity of the spliceosome.

Nature. 2013 Jan 31;493(7434):638-43. doi: 10.1038/nature11843. Epub 2013 Jan 23.

Visualizing group II intron catalysis through the stages of splicing.

Cell. 2012 Oct 26;151(3):497-507. doi: 10.1016/j.cell.2012.09.033.

The spliceosome: design principles of a dynamic RNP machine.

Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009.

Is the spliceosome a ribonucleoprotein enzyme?

Nat Struct Mol Biol. 2008 Dec;15(12):1235-7. doi: 10.1038/nsmb1208-1235.

Structural elucidation of a PRP8 core domain from the heart of the spliceosome.

Nat Struct Mol Biol. 2008 Nov;15(11):1199-205. doi: 10.1038/nsmb.1505. Epub 2008 Oct 2.

Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins.

Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13817-22. doi: 10.1073/pnas.0805960105. Epub 2008 Sep 8.

Crystal structure of a self-spliced group II intron.

Science. 2008 Apr 4;320(5872):77-82. doi: 10.1126/science.1153803.