Kovalchuk V V
Semashko Sity Hospital, St. Petersburg, Russia
Zh Nevrol Psikhiatr Im S S Korsakova. 2013;113(4):35-40.
An effect of mydocalm on muscle tone and functional rehabilitation in 1700 stroke patients (mean age 63,4 years) has been studied. Patients have been divided into two standardized groups: the basic group (850 persons who received mydocalm) and control one (850 persons who didn't receive mydocalm). The muscle tone was followed up using the Ashworth Scale, pain syndrome was assessed with the Huskisson visual analog scale and a multidimensional verbal-color pain test. The functional rehabilitation was evaluated using Barthel, Lindmark, Scandinavian and Merton & Sutton scales. Psychoemotional condition was assessed with the Beck Depression Questionnaire and the Wakefield Depression Scale, quality of life was measured by the Sickness Impact Profile. The results of the study have revealed that the use of mydocalm result in the improvement of muscle tone, decrease of pain syndrome, increase of functional rehabilitation and improvement of psychoemotional condition and the quality of life of post stroke patients. The findings of the study have demonstrated the good tolerability of mydocalm. Adverse events in the mydocalm group have been identified more rarely than in the control group.
研究了米多卡尔（mydocalm）对1700名中风患者（平均年龄63.4岁）肌肉张力及功能康复的影响。患者被分为两个标准化组：基础组（850名接受米多卡尔治疗的患者）和对照组（850名未接受米多卡尔治疗的患者）。使用Ashworth量表随访肌肉张力，用Huskisson视觉模拟量表及多维语言-颜色疼痛测试评估疼痛综合征。采用Barthel、Lindmark、斯堪的纳维亚及Merton & Sutton量表评估功能康复情况。用贝克抑郁问卷及韦克菲尔德抑郁量表评估心理情绪状况，通过疾病影响量表测量生活质量。研究结果显示，使用米多卡尔可改善中风后患者的肌肉张力、减轻疼痛综合征、提高功能康复水平、改善心理情绪状况及生活质量。该研究结果表明米多卡尔具有良好的耐受性。与对照组相比，米多卡尔组不良事件的发现更为少见。
