[慢性疼痛综合征中内源性生物调节剂抗体及其与年龄和性别的关联]

[Antibodies to endogenous bioregulators and their association with age and sex in chronic pain syndrome].

作者信息

Myagkova M A, Petrochenko S N, Morozova V S, Moseikin I A, Shypitsin V V, Polyvyanaya O Yu

机构信息

Moscow Clinical Research Center of Narcology, Moscow, Russia

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2013;113(4):41-4.

PMID:23739439

Abstract

Authors studied changes in the levels of antibodies to endogenous bioregulators (Ab) to Β-endorphin, orphanin, serotonin, dopamine and angiotensin in 36 healthy people and 109 patients with dorsopathy with chronic pain syndrome. The association of these immunological indicators with age and sex was found. It has been concluded that the levels of Ab to endogenous bioregulators may be considered as a marker of algic system pathology that does not depend on age and is sex-related.

摘要

作者研究了36名健康人和109名患有慢性疼痛综合征的背部疾病患者体内针对内源性生物调节剂（抗体）的β-内啡肽、孤啡肽、血清素、多巴胺和血管紧张素抗体水平的变化。发现了这些免疫指标与年龄和性别的关联。得出的结论是，内源性生物调节剂抗体水平可被视为不依赖于年龄且与性别相关的疼痛系统病理学标志物。