Duarte Ida Alzira Gomes, Korkes Karen Levy, Amorim Vanessa Alice M, Kobata Clarice, Buense Roberta, Lazzarini Rosana
Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, (SP), Brazil.
An Bras Dermatol. 2013 Mar-Apr;88(2):306-8. doi: 10.1590/S0365-05962013000200028.
Whether parapsoriasis represents an early stage of T-cell cutaneous lymphoma is still the subject of controversy. We evaluated the efficacy of phototherapy in the treatment of parapsoriasis and its relation with TCCL. Patients diagnosed with parapsoriasis and treated with phototherapy PUVA or UVB-NB were selected. Between 1 to 8 years following treatment the evolution of their disease was evaluated. In 62 patients the cure rate was 79.3% and 17.2% showed improvement of the lesions. Only two patients developed full blown T-cell cutaneous lymphoma. Phototherapy is an excellent treatment for parapsoriasis, with high cure rates, regardless of the type of phototherapy employed. Of the 62 patients under study, parapsoriasis showed no general tendency to progress to T-cell cutaneous lymphoma.
副银屑病是否代表T细胞皮肤淋巴瘤的早期阶段仍是一个有争议的话题。我们评估了光疗在治疗副银屑病中的疗效及其与T细胞皮肤淋巴瘤(TCCL)的关系。选取了诊断为副银屑病并接受光化学疗法(PUVA)或窄谱中波紫外线(UVB-NB)光疗的患者。在治疗后的1至8年期间,评估他们疾病的进展情况。62例患者的治愈率为79.3%,17.2%的患者皮损有改善。只有两名患者发展为典型的T细胞皮肤淋巴瘤。无论采用何种光疗类型,光疗都是治疗副银屑病的一种有效方法,治愈率高。在研究的62例患者中,副银屑病没有发展为T细胞皮肤淋巴瘤的总体趋势。