Helsinki University Eye Hospital, Helsinki, Finland.
J Refract Surg. 2013 Jun;29(6):378-82. doi: 10.3928/1081597X-20130515-01.
To investigate the effectiveness of femtosecond laser-assisted intrastromal relaxing incisions for astigmatism management and establish laser treatment parameters.
Sixteen eyes of 16 patients had regular astigmatism after penetrating keratoplasty. All sutures had been removed and the refraction was stabilized. Paired arcuate intrastromal incisions were made 180° apart within the graft stroma with a femtosecond laser preserving the epithelium. Follow-up examinations were performed at 1 week, 2 weeks, 1 month, and 3 months.
The logMAR corrected distance visual acuity (CDVA) improved from 0.50 ± 0.29 to 0.32 ± 0.23 (Snellen 20/63 to 20/40). Refractive and topographic anterior cylinders decreased from 6.8 ± 2.2 diopters (D) to 3.7 ± 1.7 D and from 9.5 ± 4.8 D to 4.4 ± 2.1 D, respectively. Stabilization of topographic cylinder was observed 1 month postoperatively. The worse the preoperative CDVA was and the higher the preoperative values for the refractive and topographic cylinders were, the higher the surgically induced changes were. Anterior side cut angles at 90° and 120° produced similar results. A bulge of incision occurred in one eye requiring compression sutures.
Significant improvement in CDVA and refractive and topographic cylinders indicated a good effect of femtosecond laser-assisted intrastromal relaxing incisions in reducing astigmatism. No advantage between 90° and 120° anterior side cut angles was found. No infections were recorded and no patient expressed discomfort.
研究飞秒激光辅助间质松解切口治疗散光的有效性,并确定激光治疗参数。
16 例(16 眼)穿透性角膜移植术后存在规则性散光且已拆除缝线、屈光状态稳定的患者纳入研究。应用飞秒激光在移植片基质内 180° 间隔制作两个配对的弧形的内皮层间松解切口,保留上皮。术后 1 周、2 周、1 个月和 3 个月进行随访检查。
对数视力矫正(logMAR)远距视力(CDVA)从 0.50±0.29 提高到 0.32±0.23(Snellen 视力 20/63 提高到 20/40)。等效球镜(refractive)和角膜地形图前向散光分别从 6.8±2.2 屈光度(D)降低至 3.7±1.7 D 和从 9.5±4.8 D 降低至 4.4±2.1 D,术后 1 个月观察到角膜地形图散光稳定。术前 CDVA 越差、等效球镜和角膜地形图前向散光越高,手术引起的变化越大。90°和 120°前侧切口角度产生相似的结果。1 只眼切口处膨出,需要加压缝线。
CDVA、等效球镜和角膜地形图散光的显著改善表明飞秒激光辅助间质松解切口在降低散光方面有良好的效果。90°和 120°前侧切口角度之间没有发现优势。未发生感染,患者均无不适。