Department of Internal Medicine, Istanbul Medical School, Istanbul University, Capa, 34390, Istanbul, Turkey.
Aging Clin Exp Res. 2013 Apr;25(1):115-7. doi: 10.1007/s40520-013-0002-4. Epub 2013 Mar 27.
Edema can be observed as side-effect of many medications, of which calcium channel blockers are the best known. Elderly people use many more medications than their younger counterparts and are usually more prone to developing medication-induced side-effects. Atypical antipsychotics have occasionally been shown to induce peripheric edema. Age is put forward as a risk factor for olanzapine-induced edema. We present here the case of an elderly man who developed upper- and lower-limb edema during use of olanzapine to emphasize its relatively frequent association with edema in the elderly.
水肿是许多药物的副作用之一，其中钙通道阻滞剂最为人所知。老年人比年轻人使用更多的药物，而且通常更容易发生药物引起的副作用。非典型抗精神病药偶尔会引起周围性水肿。年龄被认为是奥氮平引起水肿的一个危险因素。我们在这里报告一例老年男性在使用奥氮平期间出现上下肢水肿的病例，以强调其在老年人中与水肿的相对常见关联。
