Mathan Kaliaperumal, Muthukrishnan Venkatesan, Menon Vikas
Department of Psychiatry, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
J Pharmacol Pharmacother. 2015 Apr-Jun;6(2):114-5. doi: 10.4103/0976-500X.155494.
Antipsychotic-induced edema is uncommonly encountered in clinical practice. We report a case of tender pitting pre-tibial edema with olanzapine in a woman with no medical comorbidities. The peculiar distribution of edema resulted in diagnostic confusion necessitating specific investigations. Eventually, the edema resolved following complete stoppage of the drug, but caused distress to the patient and the caregiver.
抗精神病药物引起的水肿在临床实践中并不常见。我们报告一例无其他内科合并症的女性患者在使用奥氮平后出现胫骨前压痛性凹陷性水肿的病例。水肿的特殊分布导致诊断困惑，需要进行特定检查。最终，在完全停用该药物后水肿消退，但给患者及其照顾者带来了困扰。
