Brook I
Naval Hospital, Bethesda, MD.
J Med Microbiol. 1990 Jul;32(3):207-10. doi: 10.1099/00222615-32-3-207.
Bacteria were grown from 63 (69%) of 91 specimens from necrotic tumours in 63 patients. Of the tumours, 14 were abdominal, 5 pelvic, 23 of the head and neck, 4 of the lungs, 4 mediastinal, 2 lymphatic, 3 of the breast, and 8 were miscellaneous. Aerobic or facultatively anaerobic bacteria only were present in 12 (19%) specimens, anaerobes only in 10 (16%), and mixed aerobic and anaerobic bacteria in 41 (65%). A total of 83 anaerobic and 47 aerobic and facultatively anaerobic bacteria were isolated. The predominant anaerobic bacteria were Bacteroides spp. (36 isolates), and anaerobic cocci (21) and Propionibacterium acnes (22). The aerobic and facultatively anaerobic bacteria most frequently isolated were Staphylococcus aureus, alpha-haemolytic streptococci, Escherichia coli (seven isolates each), S. epidermidis, Klebsiella pneumoniae and Pseudomonas aeruginosa (five isolates each). These data demonstrate that infection of tumours is usually polymicrobial.
从63例患者坏死肿瘤的91份标本中培养出细菌的有63份（69%）。这些肿瘤中，14例位于腹部，5例位于盆腔，23例位于头颈部，4例位于肺部，4例位于纵隔，2例位于淋巴系统，3例位于乳腺，8例为其他部位。仅需氧菌或兼性厌氧菌存在于12份（19%）标本中，仅厌氧菌存在于10份（16%）标本中，需氧菌和厌氧菌混合存在于41份（65%）标本中。共分离出83株厌氧菌以及47株需氧菌和兼性厌氧菌。主要的厌氧菌为拟杆菌属（36株分离株）、厌氧球菌（21株）和痤疮丙酸杆菌（22株）。最常分离出的需氧菌和兼性厌氧菌为金黄色葡萄球菌、α-溶血性链球菌、大肠杆菌（各7株分离株）、表皮葡萄球菌、肺炎克雷伯菌和铜绿假单胞菌（各5株分离株）。这些数据表明肿瘤感染通常是多微生物感染。
