Division of Dermatology, Vanderbilt University, Nashville, Tennessee 37204, USA.
Dermatol Ther. 2013 May-Jun;26(3):197-206. doi: 10.1111/dth.12055.
Covering wounds, acute and chronic, is one of the most fundamental activities of any medical practitioner. Although wound dressings primarily serve to contain the "good" and keep out the "bad," research has characterized more specifically the sophisticated interaction between the human wound bed and its dressing counterpart. Wound dressings for today's chronic wounds come in many flavors, ranging from the classic types of moisture-retentive dressings to silver-coated varieties to biologic dressings serving as skin substitutes. Moisture-retentive dressing types include foams, films, hydrogels, hydrocolloids, and alginates. Appropriate use of these dressings can help to keep the wound bed moist, which allows for epithelial migration, angiogenesis, retention of growth factors, autolytic debridement, and maintenance of electrical gradients.
覆盖伤口,无论是急性还是慢性,是任何医疗从业者最基本的活动之一。尽管伤口敷料主要用于容纳“好的”并防止“坏的”进入,但研究已经更具体地描述了人类伤口床与其敷料之间的复杂相互作用。如今,慢性伤口的敷料有多种类型,从经典的保湿敷料到涂银敷料,再到作为皮肤替代品的生物敷料。保湿敷料类型包括泡沫、薄膜、水凝胶、水胶体和藻酸盐。适当使用这些敷料可以帮助保持伤口床湿润,从而促进上皮迁移、血管生成、生长因子的保留、自溶清创和电梯度的维持。