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湿性伤口敷料对伤口愈合时间的影响:一项荟萃分析。

Impact of moist wound dressing on wound healing time: A meta-analysis.

机构信息

Department of Anesthesia Surgery Center, Peoples Hospital of Deyang City, Deyang City, Sichuan, China.

Department of Nursing, Peoples Hospital of Deyang City, Deyang City, Sichuan, China.

出版信息

Int Wound J. 2023 Dec;20(10):4410-4421. doi: 10.1111/iwj.14319. Epub 2023 Jul 19.

Abstract

Among the assortment of available dressings aimed at promoting wound healing, moist dressings have gained significant popularity because of their ability to create an optimal environment for wound recovery. This meta-analysis seeks to compare the effects of moist dressing versus gauze dressing on wound healing time. A comprehensive literature search was conducted, encompassing publications up until April 1, 2023, across multiple databases including PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), and Cochrane Library. Stringent criteria were used to determine study inclusion and evaluate methodological quality. Statistical analyses were performed utilizing Stata 17.0. A total of 13 articles, encompassing 866 participants, were included in the analysis. The findings indicate that moist dressing surpasses gauze dressing in terms of wound healing time (standard mean difference [SMD] -2.50, 95% confidence interval [CI] -3.35 to -1.66, p < 0.01; I  = 97.24%), wound site infection rate (odds ratio [OR] 0.30, 95% CI 0.17 to 0.54, p < 0.01; I  = 39.91%), dressing change times (SMD -3.65, 95% CI -5.34 to -1.97, p < 0.01; I  = 96.48%), and cost (SMD -2.66, 95% CI -4.24 to -1.09, p < 0.01; I  = 94.90%). Subgroup analyses revealed possible variations in wound healing time based on wound types and regions. This study underscores the significant advantages associated with the use of moist dressings, including expedited wound healing, reduced infection rates, decreased frequency of dressing changes, and lower overall treatment costs.

摘要

在众多旨在促进伤口愈合的敷料中,湿性敷料因其能够为伤口恢复创造最佳环境而受到广泛关注。本荟萃分析旨在比较湿性敷料与纱布敷料对伤口愈合时间的影响。我们进行了全面的文献检索,涵盖了截至 2023 年 4 月 1 日在多个数据库(包括 PubMed、Web of Science、中国知网(CNKI)和 Cochrane 图书馆)发表的出版物。我们使用严格的标准来确定研究纳入和评估方法学质量。使用 Stata 17.0 进行统计分析。共有 13 篇文章,涵盖 866 名参与者,纳入了分析。结果表明,湿性敷料在伤口愈合时间(标准均数差 [SMD] -2.50,95%置信区间 [CI] -3.35 至 -1.66,p < 0.01;I ² = 97.24%)、伤口部位感染率(比值比 [OR] 0.30,95%CI 0.17 至 0.54,p < 0.01;I ² = 39.91%)、更换敷料次数(SMD -3.65,95%CI -5.34 至 -1.97,p < 0.01;I ² = 96.48%)和成本(SMD -2.66,95%CI -4.24 至 -1.09,p < 0.01;I ² = 94.90%)方面优于纱布敷料。亚组分析显示,根据伤口类型和部位,伤口愈合时间可能存在差异。本研究强调了使用湿性敷料的显著优势,包括加快伤口愈合、降低感染率、减少敷料更换次数和降低总体治疗成本。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b2c/10681401/9e1c14bc6e0f/IWJ-20-4410-g008.jpg

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