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绿茶提取物在化妆品配方中的应用:不仅是一种抗氧化活性成分。

The use of green tea extract in cosmetic formulations: not only an antioxidant active ingredient.

机构信息

Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of Sao Paulo, São Paulo, Brazil.

出版信息

Dermatol Ther. 2013 May-Jun;26(3):267-71. doi: 10.1111/j.1529-8019.2013.01552.x. Epub 2013 Mar 13.

Abstract

Green tea (GT) extracts contain polyphenols, known to be effective free radical scavengers, and other ingredients that could also provide benefits to the skin. This is a report on clinical studies using objective, noninvasive methods to evaluate the effects of cosmetic formulations containing GT. Experimental formulations were supplemented or not (vehicle) with 6% Camellia sinensis glycolic leaf extracts (GT). These formulations were applied to the forearm skin of 24 volunteers, and their effects were evaluated before and after 2 hours, 15 and 30 days according to the following parameters: stratum corneum water content, transepidermal water loss, skin viscoelastic-to-elastic ratio (Uv/Ue), and microrelief. The volunteers were instructed not to apply any formulation in an area of the forearm (control area). Experimental formulations (GT) increased skin moisture in the long-term study, indicating that GT has a prolonged moisturizing effect. The Uv/Ue was significantly enhanced after 30 days of topical application of the experimental formulation when compared with vehicle and control. After 15-30 days, skin microrelief was significantly improved due to a reduction in skin roughness. The results suggest that GT-containing cosmetic formulations have pronounced moisturizing effects and improve skin microrelief.

摘要

绿茶(GT)提取物含有多酚,众所周知,多酚是有效的自由基清除剂,其他成分也可能对皮肤有益。这是一份关于使用客观、非侵入性方法评估含有 GT 的化妆品配方效果的临床研究报告。实验配方用或不用(载体)6%的茶树(Camellia sinensis)乙二醇叶提取物(GT)进行补充。将这些配方应用于 24 名志愿者的前臂皮肤,根据以下参数在 2 小时、15 天和 30 天前后评估其效果:角质层水分含量、经表皮水分流失、皮肤粘弹性-弹性比(Uv/Ue)和微观粗糙度。志愿者被指示不要在前臂的一个区域涂抹任何制剂(对照区域)。在长期研究中,实验配方(GT)增加了皮肤水分,表明 GT 具有持久的保湿作用。与载体和对照相比,实验制剂局部应用 30 天后 Uv/Ue 显著增强。在 15-30 天内,由于皮肤粗糙度的降低,皮肤微观粗糙度得到了显著改善。结果表明,含有 GT 的化妆品配方具有显著的保湿效果,并改善了皮肤微观粗糙度。

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