Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of Sao Paulo, São Paulo, Brazil.
Dermatol Ther. 2013 May-Jun;26(3):267-71. doi: 10.1111/j.1529-8019.2013.01552.x. Epub 2013 Mar 13.
Green tea (GT) extracts contain polyphenols, known to be effective free radical scavengers, and other ingredients that could also provide benefits to the skin. This is a report on clinical studies using objective, noninvasive methods to evaluate the effects of cosmetic formulations containing GT. Experimental formulations were supplemented or not (vehicle) with 6% Camellia sinensis glycolic leaf extracts (GT). These formulations were applied to the forearm skin of 24 volunteers, and their effects were evaluated before and after 2 hours, 15 and 30 days according to the following parameters: stratum corneum water content, transepidermal water loss, skin viscoelastic-to-elastic ratio (Uv/Ue), and microrelief. The volunteers were instructed not to apply any formulation in an area of the forearm (control area). Experimental formulations (GT) increased skin moisture in the long-term study, indicating that GT has a prolonged moisturizing effect. The Uv/Ue was significantly enhanced after 30 days of topical application of the experimental formulation when compared with vehicle and control. After 15-30 days, skin microrelief was significantly improved due to a reduction in skin roughness. The results suggest that GT-containing cosmetic formulations have pronounced moisturizing effects and improve skin microrelief.
绿茶(GT)提取物含有多酚,众所周知,多酚是有效的自由基清除剂,其他成分也可能对皮肤有益。这是一份关于使用客观、非侵入性方法评估含有 GT 的化妆品配方效果的临床研究报告。实验配方用或不用(载体)6%的茶树(Camellia sinensis)乙二醇叶提取物(GT)进行补充。将这些配方应用于 24 名志愿者的前臂皮肤,根据以下参数在 2 小时、15 天和 30 天前后评估其效果:角质层水分含量、经表皮水分流失、皮肤粘弹性-弹性比(Uv/Ue)和微观粗糙度。志愿者被指示不要在前臂的一个区域涂抹任何制剂(对照区域)。在长期研究中,实验配方(GT)增加了皮肤水分,表明 GT 具有持久的保湿作用。与载体和对照相比,实验制剂局部应用 30 天后 Uv/Ue 显著增强。在 15-30 天内,由于皮肤粗糙度的降低,皮肤微观粗糙度得到了显著改善。结果表明,含有 GT 的化妆品配方具有显著的保湿效果,并改善了皮肤微观粗糙度。