• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

A mutation-independent therapeutic strategy for dominant dystrophic epidermolysis bullosa.

作者信息

Morgan Clare P, Allen Danny S I, Millington-Ward Sophia, O'Dwyer Gareth E, Palfi Arpad, Jane Farrar G

机构信息

Department of Genetics, Trinity College Dublin, Dublin, Ireland.

Department of Genetics, Trinity College Dublin, Dublin, Ireland.

出版信息

J Invest Dermatol. 2013 Dec;133(12):2793-2796. doi: 10.1038/jid.2013.241. Epub 2013 Jun 6.

DOI:10.1038/jid.2013.241
PMID:23743647
Abstract
摘要

相似文献

1
A mutation-independent therapeutic strategy for dominant dystrophic epidermolysis bullosa.一种针对显性营养不良性大疱性表皮松解症的非依赖突变的治疗策略。
J Invest Dermatol. 2013 Dec;133(12):2793-2796. doi: 10.1038/jid.2013.241. Epub 2013 Jun 6.
2
siRNA-mediated allele-specific inhibition of mutant type VII collagen in dominant dystrophic epidermolysis bullosa.小干扰RNA介导的显性营养不良性大疱性表皮松解症中突变VII型胶原蛋白的等位基因特异性抑制。
J Invest Dermatol. 2012 Jun;132(6):1741-3. doi: 10.1038/jid.2012.11. Epub 2012 Feb 16.
3
Meganuclease-Mediated COL7A1 Gene Correction for Recessive Dystrophic Epidermolysis Bullosa.用于隐性营养不良性大疱性表皮松解症的巨核酸酶介导的COL7A1基因校正
J Invest Dermatol. 2016 Apr;136(4):872-875. doi: 10.1016/j.jid.2015.11.028. Epub 2016 Feb 17.
4
Gene-Corrected Fibroblast Therapy for Recessive Dystrophic Epidermolysis Bullosa using a Self-Inactivating COL7A1 Retroviral Vector.使用自失活COL7A1逆转录病毒载体的基因校正成纤维细胞疗法治疗隐性营养不良性大疱性表皮松解症
J Invest Dermatol. 2016 Jul;136(7):1346-1354. doi: 10.1016/j.jid.2016.02.811. Epub 2016 Mar 16.
5
Gene therapy for recessive dystrophic epidermolysis bullosa.隐性营养不良型大疱性表皮松解症的基因治疗。
Dermatol Clin. 2010 Apr;28(2):361-6, xii. doi: 10.1016/j.det.2010.02.003.
6
Phase I/II ex vivo gene therapy clinical trial for recessive dystrophic epidermolysis bullosa using skin equivalent grafts genetically corrected with a COL7A1-encoding SIN retroviral vector (GENEGRAFT).使用编码COL7A1的SIN逆转录病毒载体(GENEGRAFT)进行基因校正的皮肤等效移植物,针对隐性营养不良性大疱性表皮松解症的I/II期离体基因治疗临床试验。
Hum Gene Ther Clin Dev. 2014 Jun;25(2):65-6. doi: 10.1089/humc.2014.2508.
7
Fibroblasts show more potential as target cells than keratinocytes in COL7A1 gene therapy of dystrophic epidermolysis bullosa.在营养不良性大疱性表皮松解症的COL7A1基因治疗中,成纤维细胞作为靶细胞比角质形成细胞更具潜力。
J Invest Dermatol. 2006 Apr;126(4):766-72. doi: 10.1038/sj.jid.5700117.
8
Footprint-free gene mutation correction in induced pluripotent stem cell (iPSC) derived from recessive dystrophic epidermolysis bullosa (RDEB) using the CRISPR/Cas9 and piggyBac transposon system.利用CRISPR/Cas9和猪尾巴转座子系统对源自隐性营养不良性大疱性表皮松解症(RDEB)的诱导多能干细胞(iPSC)进行无足迹基因突变校正。
J Dermatol Sci. 2020 Jun;98(3):163-172. doi: 10.1016/j.jdermsci.2020.04.004. Epub 2020 Apr 24.
9
Normal and gene-corrected dystrophic epidermolysis bullosa fibroblasts alone can produce type VII collagen at the basement membrane zone.正常的和经基因校正的营养不良性大疱性表皮松解症成纤维细胞自身就能在基底膜区产生VII型胶原蛋白。
J Invest Dermatol. 2003 Nov;121(5):1021-8. doi: 10.1046/j.1523-1747.2003.12571.x.
10
Recessive Dystrophic Epidermolysis Bullosa: Advances in the Laboratory Leading to New Therapies.隐性营养不良性大疱性表皮松解症:实验室进展带来新疗法
J Invest Dermatol. 2015 Jul;135(7):1705-1707. doi: 10.1038/jid.2015.149.

引用本文的文献

1
Integrated Management Strategies for Epidermolysis Bullosa: Current Insights.大疱性表皮松解症的综合管理策略:当前见解
Int J Gen Med. 2022 May 24;15:5133-5144. doi: 10.2147/IJGM.S342740. eCollection 2022.
2
Challenges in Treating Genodermatoses: New Therapies at the Horizon.遗传性皮肤病治疗面临的挑战:新疗法即将出现。
Front Pharmacol. 2022 Jan 5;12:746664. doi: 10.3389/fphar.2021.746664. eCollection 2021.
3
Clinical Perspectives of Gene-Targeted Therapies for Epidermolysis Bullosa.大疱性表皮松解症基因靶向治疗的临床前景
Dermatol Ther (Heidelb). 2021 Aug;11(4):1175-1197. doi: 10.1007/s13555-021-00561-5. Epub 2021 Jun 10.
4
Pathogenetic Therapy of Epidermolysis Bullosa: Current State and Prospects.大疱性表皮松解症的致病疗法:现状与前景
Bull Exp Biol Med. 2021 May;171(1):109-121. doi: 10.1007/s10517-021-05182-8. Epub 2021 May 29.
5
Novel and emerging therapies in the treatment of recessive dystrophic epidermolysis bullosa.隐性营养不良性大疱性表皮松解症治疗中的新型及新兴疗法。
Intractable Rare Dis Res. 2017 Feb;6(1):6-20. doi: 10.5582/irdr.2017.01005.
6
RNA-based therapies for genodermatoses.用于遗传性皮肤病的基于RNA的疗法。
Exp Dermatol. 2017 Jan;26(1):3-10. doi: 10.1111/exd.13141.