Abou Samra Waleed, Shahin Maha, El-Awady Hatem, El-Rahman Ashraf Abd, El-Toukhy Nahed
Int Ophthalmol. 2014 Apr;34(2):269-75. doi: 10.1007/s10792-013-9804-9. Epub 2013 Jun 7.
To investigate ocular blood flow changes in healthy myopic patients following laser in situ keratomileusis (LASIK) using color Doppler imaging. Sixteen eyes of 16 myopic patients were studied. LASIK was performed and intraocular pressure was raised to levels ≥65 mmHg. Color Doppler images were obtained to study the ophthalmic and central retinal arteries preoperatively and postoperatively at 1 day, 1 week, and 1 month. There was no significant correlation between patient age and preoperative ocular blood flow parameters. A significant positive correlation between the degree of myopia and the peak systolic volume of the ophthalmic artery (r = 0.6, P = 0.01) was found. A highly significant decrease in the peak systolic volume and end-diastolic volume with an increase in the resistive index of both arteries (P < 0.005) was seen at 1 day and 1 week postoperatively. There was no significant difference between the preoperative and postoperative data 1 month after the procedure. The findings of this study show temporary alterations in ocular blood flow parameters after LASIK. LASIK is an increasingly common lifestyle procedure and further studies on larger groups are still recommended.
采用彩色多普勒成像技术研究健康近视患者行准分子原位角膜磨镶术（LASIK）后眼血流变化。研究了16例近视患者的16只眼。行LASIK手术并将眼压升高至≥65 mmHg。术前及术后1天、1周和1个月获取彩色多普勒图像，以研究眼动脉和视网膜中央动脉。患者年龄与术前眼血流参数之间无显著相关性。发现近视度数与眼动脉收缩期峰值容积之间存在显著正相关（r = 0.6，P = 0.01）。术后1天和1周时，随着两条动脉阻力指数增加，收缩期峰值容积和舒张末期容积显著降低（P < 0.005）。术后1个月时术前和术后数据之间无显著差异。本研究结果表明LASIK术后眼血流参数有暂时性改变。LASIK是一种越来越常见的改善生活方式的手术，仍建议对更大样本量的群体进行进一步研究。
