Bahadir Kilavuzoglu Ayse Ebru, Bozkurt Tahir Kansu, Cosar Cemile Banu, Sener Asım Bozkurt
Department of Ophthalmology, Acibadem University School of Medicine, Acibadem Maslak Hastanesi Goz Hastaliklari Klinigi, Darussafaka Mah. Buyukdere Cad. No:40 34457, Sariyer, Istanbul, Turkey.
Umraniye Training and Research Hospital, Eye Clinic, Elmalikent Mah. Adem Yavuz Cad. No:1 34764, Umraniye, Istanbul, Turkey.
Int Ophthalmol. 2018 Aug;38(4):1541-1547. doi: 10.1007/s10792-017-0617-0. Epub 2017 Jun 24.
To describe a sample predictive model for intraocular pressure (IOP) following laser in situ keratomileusis (LASIK) for myopia and an IOP constant.
The records of patients that underwent LASIK for myopia and myopic astigmatism via WaveLight Allegretto Wave Eye-Q 400 Hz excimer laser and Hansatome XP microkeratome were retrospectively reviewed. Patients with no systemic or ocular disease other than myopia or myopic astigmatism were included in the study. Preoperative and postoperative month 1 data and intraoperative data were used to build the predictive model for IOP after LASIK. The IOP constant was calculated by subtracting the predicted IOP from preoperative IOP. The paired samples t test, Pearson's correlation analysis, curve estimation analysis, and linear regression analysis were used to evaluate the study data.
The study included 425 eyes in 214 patients with a mean age of 32 ± 7.8 years. Mean spherical equivalent of the attempted correction (SE-ac) was -3.7 ± 1.7 diopters. Mean post-LASIK decrease in IOP was 4.6 ± 2.3 mmHg. The difference between preoperative and postoperative IOP was statistically significant (P < 0.001). SE-ac, preoperative IOP, and central corneal thickness had highly significant effects on postoperative IOP, based on linear regression analysis (P < 0.001 and R = 0.043, P < 0.001 and R = 0.370, and P < 0.001 and R = 0.132, respectively). Regression model was created (F = 127.733, P < 0.001), and the adjusted R value was 0.548.
Evaluation of IOP after LASIK is important in myopic patients. The present study described a practical formula for predicting the true IOP with the aid of an IOP constant value in myopic eyes following LASIK.
描述一种用于近视患者准分子原位角膜磨镶术（LASIK）后眼压（IOP）的样本预测模型及一个眼压常数。
回顾性分析经威视 Allegretto Wave Eye-Q 400 Hz 准分子激光和 Hansatome XP 微型角膜刀行 LASIK 治疗近视及近视散光患者的病历。研究纳入除近视或近视散光外无全身或眼部疾病的患者。术前及术后 1 个月数据和术中数据用于构建 LASIK 术后眼压预测模型。眼压常数通过术前眼压减去预测眼压计算得出。采用配对样本 t 检验、Pearson 相关分析、曲线估计分析和线性回归分析评估研究数据。
该研究纳入 214 例患者的 425 只眼，平均年龄 32±7.8 岁。拟矫正的平均等效球镜度（SE-ac）为-3.7±1.7 屈光度。LASIK 术后平均眼压降低 4.6±2.3 mmHg。术前和术后眼压差异有统计学意义（P<0.001）。基于线性回归分析，SE-ac、术前眼压和中央角膜厚度对术后眼压有高度显著影响（分别为 P<0.001，R=0.043；P<0.001，R=0.370；P<0.001，R=0.132）。创建回归模型（F=127.733，P<0.001），调整后 R 值为 0.548。
评估近视患者 LASIK 术后的眼压很重要。本研究描述了一个借助眼压常数预测近视患者 LASIK 术后真实眼压的实用公式。
