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[恶性眼睑肿瘤的外科治疗]

[Surgical treatment of malignant eyelid tumors].

作者信息

Zieliński Tomasz, Pisera Paweł, Siewiera Ireneusz, Sporny Stanisław, Iljin Aleksandra

机构信息

Uniwersytet Medyczny w Łodzi, Klinika Chirurgii Plastycznej, Rekonstrukcyjnej i Estetycznej.

出版信息

Pol Merkur Lekarski. 2013 Apr;34(202):214-8.

PMID:23745328
Abstract

UNLABELLED

Eyelid tumors constitute 5 to 10% of all skin malignancies. They mostly affect the elderly, chronically exposed to sunlight. The primary treatment is radical surgical excision of the tumor. The aim of this study was the clinical and microscopical analysis of malignant eyelid tumors in treated patients, the presentation of selected reconstructive methods and the evaluation of long-term results of surgical treatment of eyelid tumors.

MATERIAL AND METHODS

The study involved 92 patients treated in 2000-2007 for malignant tumors of the eyelids. All patients underwent surgical excision of the tumor with concurrent eyelid reconstruction. The choice of reconstructive method depended on the size and location of the tumor. Histopathological evaluation was carried out specifying the type of cancer and radical surgery. The long-term results were rated on the basis of medical records and patients' examinations.

RESULTS

Tumors were located mostly within the lower eyelid 67 (70.5%) and the medial canthus 17 (17.9%). Basal cell carcinoma was found in 83 (87.3%) cases, while in 12 (12.7%) diagnosed with other, less common cancers. Histopathological verification of tumor margins revealed incomplete excision in 14 specimens (14.7%). Reoperations due to recurrent tumor was performed in 11 (15.6%) cases. Good long-term results of functionally-aesthetic reconstruction of the eyelids was observed in 84 (91.3%) patients.

CONCLUSIONS

  1. Basal cell carcinoma is the most common malignant tumor of the oculopalpebral region and originate mainly in the lower eyelid. 2. Significantly higher risk of recurrence exists in a more aggressive form of BCC (infiltrative basal-cell carcinoma) and tumors located in medial canthus. 3. The knowledge of multiple reconstruction methods allows the surgeon to choose the most appropriate one, depending on the size and location of the defect formed after excision of the tumor.
摘要

未标注

眼睑肿瘤占所有皮肤恶性肿瘤的5%至10%。它们主要影响长期暴露于阳光下的老年人。主要治疗方法是肿瘤的根治性手术切除。本研究的目的是对接受治疗的患者的恶性眼睑肿瘤进行临床和显微镜分析,介绍所选的重建方法,并评估眼睑肿瘤手术治疗的长期效果。

材料与方法

本研究纳入了2000年至2007年因眼睑恶性肿瘤接受治疗的92例患者。所有患者均接受了肿瘤的手术切除及同期眼睑重建。重建方法的选择取决于肿瘤的大小和位置。进行了组织病理学评估,明确癌症类型和根治性手术情况。根据病历和患者检查对长期效果进行评分。

结果

肿瘤大多位于下眼睑67例(70.5%)和内眦17例(17.9%)。83例(87.3%)为基底细胞癌,12例(12.7%)诊断为其他较罕见的癌症。肿瘤边缘的组织病理学检查显示14个标本(14.7%)切除不完全。11例(15.6%)因肿瘤复发进行了再次手术。84例(91.3%)患者的眼睑功能-美学重建取得了良好的长期效果。

结论

  1. 基底细胞癌是眼睑区域最常见的恶性肿瘤,主要起源于下眼睑。2. 侵袭性更强的基底细胞癌(浸润性基底细胞癌)和位于内眦的肿瘤复发风险明显更高。3. 了解多种重建方法使外科医生能够根据肿瘤切除后形成的缺损大小和位置选择最合适的方法。

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引用本文的文献

1
Clinical Characteristics and Outcome of Malignant Eyelid Tumors: A Five-Year Retrospective Study.恶性眼睑肿瘤的临床特征与转归:一项五年回顾性研究
Med Arch. 2019 Jun;73(3):209-212. doi: 10.5455/medarh.2019.73.209-212.
2
Clinicopathological analysis of recurrent basal cell carcinoma of the eyelid.眼睑复发性基底细胞癌的临床病理分析
Postepy Dermatol Alergol. 2016 Feb;33(1):42-6. doi: 10.5114/pdia.2015.48039. Epub 2016 Feb 29.