Vrabec T R, Sergott R C, Jaeger E A, Savino P J, Bosley T M
Neuro-Ophthalmology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107.
Ophthalmology. 1990 Jun;97(6):707-10. doi: 10.1016/s0161-6420(90)32518-6.
Bilateral acute visual loss characterized by cecocentral scotomas and acquired dyschromatopsia developed in a patient receiving large oral doses of ciprofloxacin hydrochloride (Cipro). The visual defects improved after cessation of this antibiotic. To our knowledge, this association has not been described previously. The use of this medication in high doses must be accompanied by careful monitoring of optic nerve function.
一名大剂量口服盐酸环丙沙星(西普乐)的患者出现了以中心暗点和后天性色觉障碍为特征的双侧急性视力丧失。停用这种抗生素后,视力缺陷有所改善。据我们所知,此前尚未描述过这种关联。大剂量使用这种药物时必须仔细监测视神经功能。