Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou, China.
Int J Gynaecol Obstet. 2013 Sep;122(3):216-8. doi: 10.1016/j.ijgo.2013.04.003. Epub 2013 Jun 5.
To determine the willingness of pregnant women in Guangzhou, China, to participate in a large-scale birth cohort study.
A cross-sectional survey was conducted of 526 pregnant women who attended their first prenatal class at Guangzhou Women and Children's Medical Center, Guangzhou, China, between September 21 and November 15, 2011. Information on demographic characteristics, willingness to participate, and preferences regarding collection procedures and incentives were analyzed.
In all, 47.9% of the women were willing to participate in a birth cohort study, whereas 23.0% refused and 29.1% were unsure. The majority of the women willing to participate (95.2%-98.4%) accepted the use of non-invasive data collection methods except for stool collection, and 85.9% would allow their offspring to participate in long-term follow-up. Willingness to participate rose to 85.2% when non-monetary incentives were offered. The most popular incentive was assessment of child development.
The willingness of pregnant Chinese women to participate in long-term observational research was similar to that reported in high-income countries. Non-monetary incentives improved their level of willingness, a finding that might inform future maternal and child health research in low- and middle-income countries.
了解中国广州孕妇参与大型出生队列研究的意愿。
2011 年 9 月 21 日至 11 月 15 日，采用横断面调查方法，对在广州妇女儿童医疗中心参加首次产前班的 526 名孕妇进行调查。分析人口统计学特征、参与意愿以及对采集程序和激励措施的偏好。
共有 47.9%的孕妇愿意参与出生队列研究，23.0%的孕妇拒绝参与，29.1%的孕妇不确定。大多数愿意参与的孕妇（95.2%-98.4%）接受非侵入性数据采集方法，但不包括粪便采集，85.9%的孕妇允许其子女参与长期随访。提供非货币激励后，参与意愿上升至 85.2%。最受欢迎的激励措施是评估儿童发育。
中国孕妇参与长期观察性研究的意愿与高收入国家相似。非货币激励措施提高了她们的参与意愿，这一发现可能为中低收入国家的母婴健康研究提供参考。
