Yamamoto Midori, Fujita Misuzu, Mori Chisato, Hata Akira
Center for Preventive Medical Sciences, Chiba University, Chiba, Japan.
Department of Public Health, Graduate School of Medicine, Chiba University, Chiba, Japan.
J Hum Genet. 2016 Sep;61(9):787-91. doi: 10.1038/jhg.2016.60. Epub 2016 Jun 2.
For a longitudinal prospective cohort study to be successful, participants' motivation to provide information must be maintained. Therefore, this study aimed to identify items that effectively promote participants' motivation. Questionnaires were mailed to 4541 mothers and expectant mothers in Chiba Prefecture, Japan who participated in a nationwide birth cohort. A total of 2387 (52.6%) responses were received. The following items were identified as primary motivating factors among our cohort: "benefits to the participants' children", "monetary compensation" and "contribution to a better future environment". More than 30% of the respondents expressed a lack of understanding regarding the study purpose and requirements for participation. About 14% were concerned about the leakage of personal information, and 13% felt burdened by having to make a long-term commitment to the study. Cluster analysis identified four groups, two of which, one with extremely low levels of motivation and the other motivated by only money or goods, lacked an understanding of the study and tended to be concerned about the associated risks and burdens. Participants in these groups were considered to be at a high risk of dropout. Therefore, implementing measures to provide participants with a better understanding of cohort studies could lead to more successful results.
为使纵向前瞻性队列研究取得成功，必须保持参与者提供信息的积极性。因此，本研究旨在确定能有效提升参与者积极性的因素。研究问卷被邮寄给了日本千叶县参与一项全国性出生队列研究的4541名母亲和准妈妈。共收到2387份回复（回复率为52.6%）。以下因素被确定为队列中主要的激励因素：“对参与者子女有益”、“金钱补偿”以及“对未来更好环境的贡献”。超过30%的受访者表示对研究目的和参与要求缺乏理解。约14%的受访者担心个人信息泄露，13%的受访者因需长期参与研究而感到有负担。聚类分析确定了四组人群，其中两组，一组积极性极低，另一组仅受金钱或物品激励，他们对研究缺乏理解，且往往担心相关风险和负担。这些组别的参与者被认为退出研究的风险很高。因此，采取措施让参与者更好地了解队列研究可能会带来更成功的结果。
