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一名健康年轻患者出现巨大室间隔动脉瘤并伴发中风:是因果关联吗?

Massive interventricular septal aneurysm and stroke in a healthy young patient: guilt by association?

作者信息

Stendahl John C, Hasan Amatul S, Simegn Mengistu A

机构信息

Department of Medicine, Hennepin County Medical Center, Minneapolis, Minnesota.

Department of Medicine, Hennepin County Medical Center, Minneapolis, Minnesota; Division of Cardiology, Hennepin County Medical Center, Minneapolis, Minnesota; Division of Cardiology, Department of Medicine, Abbott Northwestern Hospital, Minneapolis, Minnesota.

出版信息

J Stroke Cerebrovasc Dis. 2014 Mar;23(3):590-1. doi: 10.1016/j.jstrokecerebrovasdis.2013.05.010. Epub 2013 Jun 6.

DOI:10.1016/j.jstrokecerebrovasdis.2013.05.010
PMID:23747177
Abstract

Aneurysm of the membranous interventricular septum is an uncommon cardiac defect that is, on rare occasions, associated with embolic stroke. We describe here the case of an otherwise healthy, 41-year-old man who presented to the hospital with acute-onset confusion and left-sided body weakness attributed to a right middle cerebral artery ischemic stroke. He experienced a nearly complete resolution of deficits following systemic thrombolytic therapy. After an extensive workup, the presumed mechanism of stroke was a thromboembolus that originated in a massive aneurysm of the patient's membranous interventricular septum. Due to a perceived risk of surgical morbidity, the patient was managed conservatively with anticoagulation. He denied further events and reported nearly full function at follow-up.

摘要

膜性室间隔动脉瘤是一种罕见的心脏缺陷,在极少数情况下与栓塞性中风有关。我们在此描述一名41岁健康男性的病例,他因急性起病的意识模糊和左侧肢体无力入院,病因是右侧大脑中动脉缺血性中风。经全身溶栓治疗后,他的缺损几乎完全恢复。经过全面检查,推测中风的机制是血栓栓塞,起源于患者膜性室间隔的巨大动脉瘤。由于考虑到手术并发症的风险,对该患者采取抗凝保守治疗。他否认有进一步发作,并在随访中报告功能几乎完全恢复。

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引用本文的文献

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Isolated Congenital Membranous Interventricular Septal Aneurysm: A Rare Incidental Finding.孤立性先天性膜性室间隔瘤:一种罕见的偶然发现。
Cureus. 2025 Aug 12;17(8):e89890. doi: 10.7759/cureus.89890. eCollection 2025 Aug.
2
A single-center experience with 12 consecutive cases of pregnancy among patients with membranous ventricular septal aneurysm.单中心 12 例膜部室间隔瘤患者连续妊娠的经验。
BMC Pregnancy Childbirth. 2018 Jan 3;18(1):8. doi: 10.1186/s12884-017-1646-4.