DiFazio Jillian, Fletcher Daniel J
Section of Emergency and Critical Care, Cornell University Hospital for Animals, Upper Tower Road, Ithaca, NY 14853, USA.
Vet Clin North Am Small Anim Pract. 2013 Jul;43(4):915-40. doi: 10.1016/j.cvsm.2013.03.002. Epub 2013 Apr 13.
Neurologic trauma, encompassing traumatic brain injury (TBI) and acute spinal cord injury (SCI), is a cause of significant morbidity and mortality in veterinary patients. Acute SCIs occurring secondary to trauma are also common. Essential to the management of TBI and SCI is a thorough understanding of the pathophysiology of the primary and secondary injury that occurs following trauma. This article reviews the pathophysiology of this primary and secondary injury, as well as recommendations regarding clinical assessment, diagnostics, pharmacologic and nonpharmacologic therapy, and prognosis.
神经创伤,包括创伤性脑损伤(TBI)和急性脊髓损伤(SCI),是兽医患者发病和死亡的重要原因。创伤继发的急性脊髓损伤也很常见。全面了解创伤后原发性和继发性损伤的病理生理学是治疗TBI和SCI的关键。本文综述了原发性和继发性损伤的病理生理学,以及有关临床评估、诊断、药物和非药物治疗及预后的建议。