Institute of Medical Physics, University of Erlangen-Nurnberg (Friedrich-Alexander Universität Erlangen-Nürnberg), Erlangen, Germany.
Arch Phys Med Rehabil. 2013 Nov;94(11):2046-53. doi: 10.1016/j.apmr.2013.05.013. Epub 2013 Jun 6.
To determine the effect of exercise frequency on various diseases and risk factors of the elderly.
Retrospective analysis of a randomized controlled 18-month exercise trial.
University ambulatory group setting.
Community-dwelling women aged ≥65 years (N=162) in the area of Northern Bavaria.
Mixed, intense aerobic, resistance, and balance protocol for 18 months. Subjects were retrospectively subdivided into 2 groups according to their effective attendance over 18 months (>1-<2 vs ≥2-4 sessions/wk).
Bone mineral density (BMD), lean body mass, appendicular skeletal muscle mass by dual-energy x-ray absorptiometry, Framingham study-based 10-year coronary heart disease (CHD) risk, and number of falls by calendar method.
Significant differences between the low-frequency exercise group (LF-EG) and the high-frequency exercise group (HF-EG) were observed for lumbar spine BMD (HF-EG, 2.4%±2.8% vs LF-EG, 0.3%±2.2%; P<.001) and proximal femur BMD (HF-EG, 2.4%±2.8% vs LF-EG, -0.5%±1.6%; P=.014), lean body mass (1.6%±3.4% vs 0.3%±2.6%, P=.053), and appendicular skeletal muscle mass (0.9%±4.5% vs -1.3%±3.2%, P=.011). No differences between both exercise groups were observed for 10-year CHD risk (-1.94%±4.14% vs -2.00%±3.13%; P=.943) and number of falls (0.95±1.36 vs 1.03±1.21 falls/person). Comparing the LF-EG with the less active control group (n=47), only nonsignificant effects for fall number (P=.065) and 10-year CHD risk (P=.178) were evaluated.
Although this result might not be generalizable across all exercise types and cohorts, it indicates that an overall exercise frequency of at least 2 sessions/wk may be crucial for impacting bone and muscle mass of elderly subjects.
确定运动频率对老年人各种疾病和危险因素的影响。
回顾性分析一项为期 18 个月的随机对照运动试验。
巴伐利亚北部大学门诊组。
社区居住的≥65 岁女性(N=162)。
18 个月的混合、高强度有氧、阻力和平衡方案。根据 18 个月内的有效出勤率(>1-<2 与≥2-4 次/周),将受试者回顾性地分为 2 组。
骨密度(BMD)、瘦体重、双能 X 射线吸收法测定的四肢骨骼肌质量、弗雷明汉研究的 10 年冠心病(CHD)风险和日历法的跌倒次数。
低频率运动组(LF-EG)和高频率运动组(HF-EG)之间在腰椎 BMD(HF-EG,2.4%±2.8% vs LF-EG,0.3%±2.2%;P<.001)和股骨近端 BMD(HF-EG,2.4%±2.8% vs LF-EG,-0.5%±1.6%;P=.014)、瘦体重(1.6%±3.4% vs 0.3%±2.6%,P=.053)和四肢骨骼肌质量(0.9%±4.5% vs -1.3%±3.2%,P=.011)方面存在显著差异。两组运动组之间在 10 年 CHD 风险(-1.94%±4.14% vs -2.00%±3.13%;P=.943)和跌倒次数(0.95±1.36 vs 1.03±1.21 次/人)方面无差异。将 LF-EG 与活动量较少的对照组(n=47)进行比较,仅在跌倒次数(P=.065)和 10 年 CHD 风险(P=.178)方面有非显著差异。
尽管这一结果可能不适用于所有运动类型和队列,但它表明,老年人至少每周进行 2 次运动可能对骨量和肌肉量产生重要影响。