BioProcess Technology Consultants, 12 Gill Street, Suite 5450, Woburn, MA, 01801, USA,
Adv Biochem Eng Biotechnol. 2014;139:185-225. doi: 10.1007/10_2013_215.
: With worldwide sales of biopharmaceuticals increasing each year and continuing growth on the horizon, the manufacture of mammalian biopharmaceuticals has become a major global enterprise. We describe the current and future industry wide supply of manufacturing capacity with regard to capacity type, distribution, and geographic location. Bioreactor capacity and the use of single-use products for biomanufacturing are also profiled. An analysis of the use of this capacity is performed, including a discussion of current trends that will influence capacity growth, availability, and utilization in the coming years.
随着生物制药的全球销售额逐年增长，并且前景继续增长，哺乳动物生物制药的制造已经成为一个主要的全球企业。我们描述了目前和未来的行业供应制造能力，包括能力类型、分布和地理位置。生物反应器的容量和一次性产品在生物制造中的应用也进行了概述。对这一能力的使用情况进行了分析，包括讨论了未来几年将影响产能增长、供应和利用的当前趋势。
