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[Current status of chemotherapy for colonic, rectal and anal carcinoma].

作者信息

Herrmann R

机构信息

Abteilung Inner Medizin, Universitätsklinikum Rudolf Virchow der Freien Universität Berlin, Standort Charlottenburg.

出版信息

Schweiz Rundsch Med Prax. 1990 Jul 17;79(29-30):896-8.

PMID:2374860
Abstract

Despite great efforts chemotherapeutic results of metastatic colorectal cancer are still unsatisfactory. In general, single agent treatment with 5-fluorouracil is the standard. The combination of 5-fluorouracil and folinic acid, however, shows favorable preliminary results which can be expected to lead to a small progress in this area. During the last several years the treatment strategy of squamous cell cancer of the anus has changed profoundly. In most patients radical surgery with colostomy has become unnecessary. With combined simultaneous chemotherapy and radiotherapy about 80% of all patients can achieve long term disease free survival.

摘要

相似文献

1
[Current status of chemotherapy for colonic, rectal and anal carcinoma].
Schweiz Rundsch Med Prax. 1990 Jul 17;79(29-30):896-8.
2
Clinical studies of biochemical modulation of 5-fluorouracil by leucovorin in patients with advanced colorectal cancer by the North Central Cancer Treatment Group and Mayo Clinic.由北中部癌症治疗组和梅奥诊所开展的关于亚叶酸对晚期结直肠癌患者5-氟尿嘧啶进行生化调节的临床研究。
NCI Monogr. 1987(5):185-8.
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Tumor site predicts outcome after radiochemotherapy in squamous-cell carcinoma of the anal region: long-term results of 101 patients.肿瘤部位可预测肛管鳞状细胞癌放化疗后的预后:101例患者的长期结果
Dis Colon Rectum. 2005 Sep;48(9):1742-51. doi: 10.1007/s10350-005-0098-5.
4
[Up-date of the chemotherapy of carcinoma of the colo-rectum: our experience with 5-fluorouracil and folinic acid in high doses].[结直肠癌化疗的最新进展:我们使用大剂量5-氟尿嘧啶和亚叶酸的经验]
Clin Ter. 1984 Aug 31;110(4):327-39.
5
[Treatment of advanced colonic and rectal adenocarcinoma: combination of 5-FU and high-dose folinic acid].
Bull Cancer. 1983;70(5):434-6.
6
Overview of current status and future direction of clinical trials with 5-fluorouracil in combination with folinic acid.5-氟尿嘧啶联合亚叶酸钙临床试验的现状与未来方向概述
Cancer Treat Rep. 1987 Dec;71(12):1249-64.
7
Sequential 5-fluorouracil, methotrexate, and calcium leucovorin in metastatic colorectal cancer.转移性结直肠癌中5-氟尿嘧啶、甲氨蝶呤和亚叶酸钙的序贯治疗
Wis Med J. 1988 May;87(5):20-3.
8
Double modulation with methotrexate and L-leucovorin of weekly 24- hour fluorouracil infusion in fluorouracil-refractory colorectal cancer.
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[Surgery and multidisciplinary treatment for colorectal cancer].[结直肠癌的手术及多学科治疗]
Gan To Kagaku Ryoho. 1998 Jan;25(2):208-15.
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Anorectal squamous cell carcinoma at Mississippi Baptist Medical Center: results of the last five years of the Nigro schedule.密西西比浸礼会医疗中心的肛管鳞状细胞癌:尼格罗方案过去五年的结果
J Miss State Med Assoc. 1985 Oct;26(10):283-4.

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