Urun Yuksel, Kankaya Duygu, Koral Lokman, Yalcin Bulent, Karabork Ayca, Ceyhan Koray, Boruban Melih Cem, Utkan Güngör, Demirkazik Ahmet
Department of Medical Oncology, Ankara University Faculty of Medicine, Ankara, Turkey.
Tumori. 2013 Mar-Apr;99(2):e65-9. doi: 10.1177/030089161309900231.
Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm that originates from follicular dendritic cells in lymphoid follicles. FDCS has been increasingly reported in recent years. However, data on FDCS are mostly based on single case reports or case series and its natural history and standard treatment are not clear. To increase the understanding of this rare disease, we report our experience of three cases of FDCS with an analysis of the morphological and immunophenotypic characteristics, clinical course, treatment options and response to treatment. In addition, we reviewed the literature on FDCS.
滤泡性树突状细胞肉瘤(FDCS)是一种起源于淋巴滤泡中滤泡性树突状细胞的罕见肿瘤。近年来,FDCS的报道日益增多。然而,关于FDCS的数据大多基于单病例报告或病例系列,其自然病史和标准治疗尚不清楚。为了增进对这种罕见疾病的了解,我们报告了3例FDCS的诊治经验,并分析了其形态学和免疫表型特征、临床病程、治疗选择及治疗反应。此外,我们还回顾了关于FDCS的文献。