Department of Chemistry, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Chem Asian J. 2013 Sep;8(9):2175-81. doi: 10.1002/asia.201300356. Epub 2013 Jun 7.
An efficient method for the one-pot synthesis of substituted phenanthridinone derivatives from N-methoxybenzamides and aryltriethoxysilanes through rhodium-catalyzed dual C-H bond activation and annulation reactions is described. A double-cycle mechanism is proposed to account for this catalytic reaction. In addition, isotope-labeling studies were performed to understand the intimate mechanism of the reaction.
描述了一种从 N-甲氧基苯甲酰胺和芳基三乙氧基硅烷通过铑催化的双重 C-H 键活化和环化反应一锅合成取代菲啶酮衍生物的有效方法。提出了双循环机制来解释这种催化反应。此外，还进行了同位素标记研究以了解反应的详细机理。
