School of Psychology and Psychiatry, Monash University, Melbourne, Australia.
Psychooncology. 2013 Nov;22(11):2478-86. doi: 10.1002/pon.3310. Epub 2013 Jun 7.
This study aimed to estimate the proportion of patients with prostate cancer (PCa) meeting the National Physical Activity Guidelines of Australia (NPAGA) and determine sociodemographic and medical factors associated with meeting these guidelines. Secondary aims included examining physical activity (PA) levels by treatment type and domain (leisure, work, transport and domestic) and establishing a predictive model of the likelihood that men with PCa would meet NPAGA.
A questionnaire was mailed to 638 men with PCa attending for treatment at the Alfred, Cabrini or Latrobe Regional Hospitals during 2010 and 2011, with a response rate of 59%. Measures included International Physical Activity Questionnaire, Hospital Anxiety and Depression Scale, Functional Assessment of Cancer Therapy - Prostate and sociodemographic items. Inclusion criteria were English speaking men aged 40 to 80 years, who had undergone radiotherapy (RT) between 9 and 30 months prior to the survey.
Of 356 men with PCa, less than half were meeting NPAGA (41.9%). Lower education and quality of life (QoL), a higher number of comorbid conditions and symptoms of depression and anxiety were associated with decreased leisure-time PA. Patients treated with androgen deprivation therapy were significantly less active than patients treated with RT only. Logistic regression analyses indicated that the likelihood of meeting NPAGA was significantly lower with higher levels of depressive symptoms and lower levels of education.
Meeting NPAGA is associated with higher QoL and psychosocial well-being in men with PCa. These findings contribute important information for targeting PA interventions to PCa survivors.
本研究旨在评估符合澳大利亚国家体力活动指南（NPAGA）的前列腺癌（PCa）患者比例，并确定与符合这些指南相关的社会人口学和医学因素。次要目标包括检查按治疗类型和领域（休闲、工作、交通和家庭）划分的体力活动（PA）水平，并建立一个预测男性 PCa 患者符合 NPAGA 可能性的模型。
2010 年至 2011 年期间，向在 Alfred、Cabrini 或 Latrobe 地区医院接受治疗的 638 名 PCa 男性患者邮寄了一份问卷，回复率为 59%。测量方法包括国际体力活动问卷、医院焦虑和抑郁量表、癌症治疗功能评估-前列腺和社会人口学项目。纳入标准为年龄在 40 至 80 岁之间、在调查前 9 至 30 个月接受过放疗（RT）的英语男性。
在 356 名 PCa 患者中，不到一半的人符合 NPAGA（41.9%）。较低的教育程度和生活质量（QoL）、更多的合并症以及抑郁和焦虑症状与休闲时间 PA 减少有关。接受雄激素剥夺治疗的患者明显比仅接受 RT 治疗的患者活动量少。逻辑回归分析表明，抑郁症状水平较高和教育程度较低与符合 NPAGA 的可能性显著降低相关。
符合 NPAGA 与 PCa 患者的更高 QoL 和心理社会健康相关。这些发现为针对 PCa 幸存者的 PA 干预措施提供了重要信息。
