Harken A H, Gabel R A, Fencl V, Moore F D
Arch Surg. 1975 Jul;110(7):819-21. doi: 10.1001/archsurg.1975.01360130051010.
Intravenous infusion of hydrochloric acid was used as a safe, effective, and quantitative method for correction of metabolic alkalosis in two patients. The first shows the risks of intravenously administered ammonium chloride, the currently available alternative to hydrochloric acid therapy. The second shows the efficacy of intravenously administered hydrochloric acid. While breathing spontaneously throughout the period of severe alkalosis, this patient showed compensatory hypoventilation with conspicuous increase in arterial carbon dioxide pressure. Normal spontaneous ventilation returned with correction of the metabolic alkalosis.
静脉输注盐酸被用作一种安全、有效且定量的方法来纠正两名患者的代谢性碱中毒。第一个案例展示了静脉注射氯化铵(目前盐酸治疗的替代方法)的风险。第二个案例展示了静脉注射盐酸的疗效。在严重碱中毒期间该患者一直自主呼吸,表现出代偿性通气不足,动脉二氧化碳分压显著升高。随着代谢性碱中毒的纠正,恢复了正常的自主通气。