Abdul Rahman Wan Faiziah Wan, Md Hashim Mohd Nizam, Win Thin Thin, Bakrin Ikmal Hisyam
Department of Pathology, Universiti Sains Malaysia, KotaBharu, Kelantan, Malaysia.
BMJ Case Rep. 2013 Jun 6;2013:bcr2013010001. doi: 10.1136/bcr-2013-010001.
Solid variant of papillary thyroid carcinoma (PTC) is a rare, poorly characterised variant and predominantly reported in children with a history of radiation exposure. This variant has a high propensity for extra-thyroidal extension and cervical lymph node metastases. A 14-year-old Malay girl who had no history of radiation exposure, presented with multiple cervical lymphadenopathy and it was clinically suspicious for tuberculosis or lymphoma. An incisional biopsy revealed a metastatic PTC. The patient underwent total thyroidectomy with bilateral lateral neck dissection and histopathology report was solid variant of PTC. Whole-body I(131) scan was performed which revealed an intense tracer uptake in the neck. She was planned for radioactive iodine ablation and now on regular follow-up for monitoring of possible tumour metastasis.
甲状腺乳头状癌实性变体（PTC）是一种罕见的、特征描述较少的变体，主要见于有辐射暴露史的儿童。这种变体具有较高的甲状腺外扩展和颈部淋巴结转移倾向。一名14岁无辐射暴露史的马来女孩，出现多处颈部淋巴结肿大，临床上怀疑为结核病或淋巴瘤。切开活检显示为转移性PTC。患者接受了全甲状腺切除术及双侧颈部侧方淋巴结清扫术，组织病理学报告为PTC实性变体。进行了全身I（131）扫描，结果显示颈部有强烈的示踪剂摄取。她计划接受放射性碘消融治疗，目前正在定期随访以监测可能的肿瘤转移。
