Gazi Emine, Altun Burak, Temiz Ahmet, Colkesen Yucel
Department of Cardiology, Canakkale Onsekiz Mart University, Canakkale, Turkey.
BMJ Case Rep. 2013 Jun 7;2013:bcr2013009917. doi: 10.1136/bcr-2013-009917.
Prosthetic heart valve thrombosis is a rare but serious complication. Surgery is the first-line therapy in symptomatic obstructive mechanical valve thrombosis, thrombolytic therapy has been used as an alternative to surgical treatment. In this case report we described a 47-year-old woman who had undergone coronary artery bypass graft and mitral valve replacement operation 9 months ago. A thrombus was detected on the prosthetic mitral valve with high transmitral gradient by transoesophageal echocardiography. Tissue plasminogen activator treatment was administered successfully. The gradient was improved on prosthetic mitral valve and embolic complications or bleeding were not occurred.
人工心脏瓣膜血栓形成是一种罕见但严重的并发症。手术是有症状的梗阻性机械瓣膜血栓形成的一线治疗方法，溶栓治疗已被用作手术治疗的替代方法。在本病例报告中，我们描述了一名47岁的女性，她在9个月前接受了冠状动脉搭桥术和二尖瓣置换手术。经食管超声心动图检查发现人工二尖瓣上有血栓，二尖瓣跨瓣压差较高。成功给予组织纤溶酶原激活剂治疗。人工二尖瓣的压差得到改善，未发生栓塞并发症或出血。
