Koban Cornel, Neuß Michael, Tambor Grit, Hölschermann Frank, Butter Christian
Immanuel Hospital Bernau Brandenburg Heart Center, Medical School Brandenburg, Ladeburger Straße 17, 16321 Bernau, Germany.
Case Rep Cardiol. 2016;2016:6809263. doi: 10.1155/2016/6809263. Epub 2016 May 26.
Prosthetic valve thrombosis is one of the most severe complications after surgical valve replacement. There are many possible presentations: from asymptomatic to life-threatening complications. We report on a 61-year-old female patient with prosthetic replacement of the aortic and mitral valve in the in-house department of cardiac surgery 3 months ago. The patient was suffering from aphasia during 5 minutes in domesticity. After her presentation in the emergency room, the echocardiographic examination revealed a thrombotic formation of the prosthetic mitral valve. At presentation, the anticoagulation was outside the effective range (INR: 1.7). A successful thrombolytic therapy with the plasminogen activator urokinase was begun with complete resolution of the thrombus.
人工瓣膜血栓形成是心脏瓣膜置换术后最严重的并发症之一。其表现形式多样：从无症状到危及生命的并发症。我们报告一名61岁女性患者，3个月前在本院心脏外科接受了主动脉瓣和二尖瓣置换术。患者在家中出现了5分钟的失语症状。在其被送往急诊室后，超声心动图检查显示人工二尖瓣有血栓形成。就诊时，抗凝治疗不在有效范围内（国际标准化比值：1.7）。开始使用纤溶酶原激活剂尿激酶进行成功的溶栓治疗，血栓完全溶解。
