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安卡非德止血剂局部应用于一名患有胃十二指肠淀粉样变性并发胃肠道出血的患者。

Topical application of ankaferd hemostat in a patient with gastroduodenal amyloidosis complicated with gastrointestinal bleeding.

作者信息

Beyazit Yavuz, Onder Fatih Oguz, Torun Serkan, Tas Adnan, Purnak Tugrul, Tenlik Ilyas, Turhan Nesrin

机构信息

aDepartment of Gastroenterology, Turkiye Yuksek Ihtisas Training and Research Hospital bDepartment of Gastroenterology, Ankara Education and Research Hospital cDepartment of Gastroenterology, Ankara Numune Education and Research Hospital dDepartment of Pathology, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey.

出版信息

Blood Coagul Fibrinolysis. 2013 Oct;24(7):762-5. doi: 10.1097/MBC.0b013e328362d996.

DOI:10.1097/MBC.0b013e328362d996
PMID:23751610
Abstract

Amyloidosis rarely manifests itself as gastrointestinal hemorrhage, especially in the absence of systemic involvement. Despite urgent endoscopic and/or pharmacological therapy, bleeding due to gastric amyloidosis usually recurs after a short period and has considerable morbidity and mortality rates, even in patients undergoing gastrointestinal surgery. For this reason, there is a need for a therapeutic armamentarium for such cases that is effective, easily applicable and has minimal side effects. In this respect, ankaferd blood stopper (ABS) offers a well tolerated and effective alternative approach for these patients. Herein we would like to report a 77-year-old man who had massive bleeding from a gastric ulcer complicating primary gastroduodenal amyloidosis, in whom topical ABS was successfully applied.

摘要

淀粉样变性很少表现为胃肠道出血,尤其是在无全身受累的情况下。尽管进行了紧急内镜和/或药物治疗,但胃淀粉样变性引起的出血通常在短时间后复发,并且具有相当高的发病率和死亡率,即使是接受胃肠道手术的患者也是如此。因此,对于此类病例,需要一种有效、易于应用且副作用最小的治疗手段。在这方面,安卡福得止血剂(ABS)为这些患者提供了一种耐受性良好且有效的替代方法。在此,我们报告一名77岁男性,其原发性胃十二指肠淀粉样变性合并胃溃疡导致大量出血,局部应用ABS成功止血。

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