一种计算酸碱状态的简单方法。

A simple method for computing acid-base state.

作者信息

Blackburn J P, Preston T D, Strickland D A

出版信息

Br J Anaesth. 1975 Apr;47(4):500-4. doi: 10.1093/bja/47.4.500.

DOI:10.1093/bja/47.4.500

Abstract

Simple methods are described for computing the variables derived from the Siggaard-Andersen nomogram, where the in vitro buffer line is either established by direct measurement or calculated from measurements of pH, Pco2 and haemoglobin. Calculations are performed using the equation of the pH-log Pco2 buffer line, the Henderson-Hasselbalch equation, and the polynomials: BE=-38.402+1.8970 (SB)-0.013342 (SB)-2 m-equiv/litre; SL=-69.046+17.377 (pH40)-1.1121 (pH40)-2; SH=-123.30+31.357 (pH40)-2.0143 (pH40)-2. Then haemoglobin=7.5 (1+(S-SL)/(SH-SL)) G/100 ml, where S is the slope of the buffer line. Results are sufficiently accurate for clinical purposes.

摘要

本文描述了一些简单方法，用于计算从西格gaard - 安德森列线图得出的变量，其中体外缓冲线可通过直接测量确定，或根据pH、二氧化碳分压（Pco2）和血红蛋白的测量值计算得出。计算使用pH - log Pco2缓冲线方程、亨德森 - 哈塞尔巴尔赫方程以及多项式：碱剩余（BE）=-38.402 + 1.8970（标准碳酸氢盐（SB））- 0.013342（SB）² 毫当量/升；斜率下限（SL）=-69.046 + 17.377（pH40）- 1.1121（pH40）²；斜率上限（SH）=-123.30 + 31.357（pH40）- 2.0143（pH40）²。然后血红蛋白=7.5（1 +（S - SL）/（SH - SL））克/100毫升，其中S是缓冲线的斜率。结果对于临床目的而言足够准确。