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[对苯齐巨林潜在滥用情况的在线报道分析]

[Analysis of online reports on the potential misuse of benzidamine].

作者信息

Schifano Fabrizio, Corazza Ornella, Marchi Alessandro, Di Melchiorre Giuditta, Sferrazza Elias, Enea Aurora, Davey Zoe, Blaszko Ursula, Deluca Paolo

机构信息

School of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom.

出版信息

Riv Psichiatr. 2013 May-Jun;48(3):182-6. doi: 10.1708/1292.14286.

DOI:10.1708/1292.14286
PMID:23752801
Abstract

Benzydamine/Tantum Rosa is a drug for external use. It is typically available in Europe, without the need of a medical prescription, for the treatment of vaginal inflammatory processes. Between December 2009 and January 2010, the Milan and Pavia (I) Poison Centres have identified some 50 cases of inappropriate benzydamine ingestion. Reasons for this misuse have been attributed to an allegedly misleading television advert. However, the recreational misuse of benzydamine is a well-known phenomenon in Brazil and in some EU countries as well, notably in Poland and Romania. It is here suggested that the recent increase in benzydamine misuse reports in Italy may well be associated with a parallel increase in level of online information regarding the molecule potential for misuse. According to the online reports, benzydamine is typically taken at a dosage of 1-4 sachets, dissolved in water and ingested orally. Its intake may be associated with hallucinations (mostly visual), sleeping disorders and euphoria. Only future, prospective, studies will confirm and better describe the benzydamine misuse potential.

摘要

苄达明/坦通蔷薇是一种外用药物。在欧洲,它通常无需医生处方即可获得,用于治疗阴道炎症。2009年12月至2010年1月期间,米兰和帕维亚(意大利)中毒控制中心确认了约50例不当摄入苄达明的病例。这种误用的原因被归咎于一则据称具有误导性的电视广告。然而,苄达明的娱乐性误用在巴西以及一些欧盟国家也是一个众所周知的现象,尤其是在波兰和罗马尼亚。这里有人指出,意大利近期苄达明误用报告的增加很可能与关于该分子误用可能性的在线信息水平的同步上升有关。根据在线报告,苄达明通常以1 - 4包的剂量服用,溶于水后口服。其摄入可能会导致幻觉(主要是视觉方面)、睡眠障碍和欣快感。只有未来的前瞻性研究才能证实并更好地描述苄达明的误用可能性。

相似文献

1
[Analysis of online reports on the potential misuse of benzidamine].[对苯齐巨林潜在滥用情况的在线报道分析]
Riv Psichiatr. 2013 May-Jun;48(3):182-6. doi: 10.1708/1292.14286.
2
Recreational use of benzydamine as a hallucinogen among street youth in Brazil.巴西街头青年将苯佐卡因作为迷幻剂滥用。
Braz J Psychiatry. 2009 Sep;31(3):208-13. doi: 10.1590/s1516-44462009000300005.
3
[Photocontact allergy caused by benzydamine (Tantum)].[苄达明(坦通)引起的光接触性过敏]
Hautarzt. 1989 Dec;40(12):771-3.
4
Recreational abuse with benzydamine hydrochloride (tantum rosa).盐酸苄达明(坦通玫瑰)的娱乐性滥用。
Clin Toxicol (Phila). 2007;45(2):198-9. doi: 10.1080/15563650600981210.
5
[Use abusive of benzydamine in Brazil: an overview in pharmacovigilance].[巴西对苄达明的滥用:药物警戒概述]
Cien Saude Colet. 2010 May;15(3):717-24. doi: 10.1590/s1413-81232010000300014.
6
Ingestions of benzydamine-containing vaginal preparations.含苄达明的阴道制剂的摄入。
Clin Toxicol (Phila). 2009 Feb;47(2):145-9. doi: 10.1080/15563650801938670.
7
Prescription drug misuse: is technology friend or foe?处方药滥用:技术是朋友还是敌人?
Drug Alcohol Rev. 2009 Jan;28(1):81-6. doi: 10.1111/j.1465-3362.2008.00004.x.
8
Benzydamine Hydrochloride (Tantum) in the management of oral inflammatory conditions.
J Can Dent Assoc. 1995 Feb;61(2):127-34.
9
[Benzidamine in the topical treatment of vaginitis caused by Gardnerella vaginalis].
Minerva Ginecol. 1992 Nov;44(11):573-84.
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[Value of benzydamine, the first anti-inflammatory vaginal solution].[首款抗炎阴道溶液——苄达明的价值]
Rev Fr Gynecol Obstet. 1989 Nov;84(11):779-81.

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