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[不同临床类型和形态学形式的原发性慢性肾小球肾炎患者的产科及新生儿并发症]

[Obstetric and neonatal complications in patients with various clinical types and morphologic forms of primary chronic glomerulonephritis].

作者信息

Diadyk A I, Vasilenko I V, Bagriĭ A E, Akimova I K, Iarovaia N F, Chernykh O S

出版信息

Akush Ginekol (Mosk). 1990 Mar(3):49-52.

PMID:2375481
Abstract

Clinical progress and outcomes of 151 pregnancies have been evaluated in 123 patients with chronic primary glomerulonephritis (GN). The incidence of gestational and neonatal complications was evaluated for a relationship with preconception findings of proteinuria, hematuria, arterial pressure, blood creatinine and, in 45 women, histological patterns of disease. Major preconception proteinuria (over 3 g/day), hypertension, decreased renal function and especially clustering of these findings were prognostically poor. Gestational progress and outcomes in mesangiocapillary GN were worse as compared with mesangial proliferative GN.

摘要

对123例慢性原发性肾小球肾炎(GN)患者的151次妊娠的临床进展和结局进行了评估。评估了妊娠和新生儿并发症的发生率与孕前蛋白尿、血尿、动脉压、血肌酐的检查结果以及45名女性的疾病组织学模式之间的关系。孕前大量蛋白尿(超过3g/天)、高血压、肾功能下降,尤其是这些表现同时出现,预后较差。与系膜增生性肾小球肾炎相比,系膜毛细血管性肾小球肾炎的妊娠进展和结局更差。

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