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甲状腺滤泡状癌术后放射性碘消融治疗后的肌病

Myopathy following postoperative ablative radioiodine for follicular carcinoma of the thyroid.

作者信息

Price Hermione C, Jayagopal Vijay

机构信息

Centre for Diabetes and Endocrinology, York Hospital, York, UK.

出版信息

Int Med Case Rep J. 2009 Mar 19;2:11-3. doi: 10.2147/imcrj.s5254. Print 2009.

DOI:10.2147/imcrj.s5254
PMID:23754875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3658207/
Abstract

We highlight a case of disabling myopathy following radioablative iodine treatment for follicular carcinoma of the thyroid. A 34-year-old man presented with a tender neck swelling, ultrasound and biopsy were suggestive of thyroid malignancy. Thyroidectomy was undertaken and histology confirmed follicular carcinoma of the thyroid. Treatment with ablative radioiodine followed and within days the patient developed disabling myopathy. Investigations to date do not reveal any other cause for the myopathy and there is no evidence to suggest that this is a paraneoplastic phenomenon. We believe this is the first reported case of ablative radioiodine-induced mypoathy.

摘要

我们着重介绍了一例因放射性碘治疗甲状腺滤泡癌后发生的致残性肌病。一名34岁男性患者出现颈部压痛性肿胀,超声检查和活检提示甲状腺恶性肿瘤。遂行甲状腺切除术,组织学检查确诊为甲状腺滤泡癌。随后进行了放射性碘消融治疗,数天内患者出现了致残性肌病。迄今为止的检查未发现该肌病的其他病因,也没有证据表明这是一种副肿瘤现象。我们认为这是首例报道的放射性碘消融诱发的肌病。

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